The PDH complex is a logical point of regulation in metabolism, as it links two majorcatabolic processes. Answer the following regarding the complex:a) Explain the advantage of E1, E2 and E3 working as a complex as opposed toseparately.b) Explain the purpose of each of the three enzymes and their associated cofactors.c) NADH can inhibit the PDH complex directly or indirectly. What is the purpose ofinhibition by NADH?d) Explain the differences between direct and indirect inhibition by NADH. Be sureto indicate the components involved and the mechanism of inhibition (impact ontarget component).

Cellular respiration is a collection of three metabolic pathways that generate ATP the energy…

Answered: The PDH complex is a logical point of…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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