The p53 pathway is important for regulating the cell cycle. In a normal cell, there is a protein called mdm2 that can bind to p53 and deactivate it. A diseased individual has a mutation in the gene that codes for mdm2, resulting in an mdm2 protein that is less able to bind to p53. Will this mutation increase, decrease, or cause no change in the rate of cell death? Explain.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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The p53 pathway is important for regulating the cell cycle. In a normal cell, there is a protein called mdm2 that can bind to p53 and deactivate it. A diseased individual has a
mutation in the gene that codes for mdm2, resulting in an mdm2 protein that is less able to bind to p53. Will this mutation increase, decrease, or cause no change in the rate of cell death? Explain. 

 

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