The origin of genes that have new functions often involves the divergence of gene duplicates.Duplicates can arise via several mechanisms. a. One mechanism of gene duplication is retrotransposition, the insertion into the genome of DNA produced by reverse transcription of a messenger RNA. These gene duplicates are often dead on arrival: they are pseudogenes as soon as they are formed. Why are such duplicates so often dead on arrival? b. A second mechanism of gene duplication occurs via unequal crossing over during meiosis. Gene duplicates formed this way are functional more often than when they arise by reverse transcription. Why is that? c. If a gene duplicate is initially functional, what are its possible ultimate fates? Which is most likely,and why?
Gene Interactions
When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.
Gene Expression
Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.
The origin of genes that have new functions often involves the divergence of gene duplicates.Duplicates can arise via several mechanisms.
a. One mechanism of gene duplication is retrotransposition, the insertion into the genome of DNA produced by reverse transcription of a messenger RNA. These gene duplicates are often dead on arrival: they are pseudogenes as soon as they are formed. Why are such duplicates so often dead on arrival?
b. A second mechanism of gene duplication occurs via unequal crossing over during meiosis. Gene duplicates formed this way are functional more often than when they arise by reverse transcription. Why is that?
c. If a gene duplicate is initially functional, what are its possible ultimate fates? Which is most likely,and why?
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