The Michaelis-Menten equation models the hyperbolic relationship between [S] and the initial reaction rate Vo for an enzyme-catalyzed, single-substrate reaction E + SES → E + P. The model can be more readily understood when comparing three conditions: [S] << Km, [S] = Km, and [S] >> Km. Match each statement with the condition that it describes. Note that "rate" refers to initial velocity Vo where steady state conditions are assumed. [Etotal] refers to the total enzyme Concentration and [Efree] refers to the concentration of free enzyme. [S] << Km [ES] is much lower than [Efree]. [S] = Km [Efree] is equal to [ES]. [S] >> Km Almost all active sites will be filled. Not true for any of these conditions Increasing [Etotall will lower Km.
The Michaelis-Menten equation models the hyperbolic relationship between [S] and the initial reaction rate Vo for an enzyme-catalyzed, single-substrate reaction E + SES → E + P. The model can be more readily understood when comparing three conditions: [S] << Km, [S] = Km, and [S] >> Km. Match each statement with the condition that it describes. Note that "rate" refers to initial velocity Vo where steady state conditions are assumed. [Etotal] refers to the total enzyme Concentration and [Efree] refers to the concentration of free enzyme. [S] << Km [ES] is much lower than [Efree]. [S] = Km [Efree] is equal to [ES]. [S] >> Km Almost all active sites will be filled. Not true for any of these conditions Increasing [Etotall will lower Km.
Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter23: Fatty Acid Catabolism
Section: Chapter Questions
Problem 21P: Using the ActiveModel for enoyl-CoA dehydratase, give an example of a case in which conserved...
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![The Michaelis-Menten equation models the hyperbolic relationship between [S] and the initial reaction rate V₁ for an
enzyme-catalyzed, single-substrate reaction E + S ⇒ ES →→ E + P. The model can be more readily understood when
comparing three conditions: [S] << Km, [S] = Km, and [S] >> Km.
Match each statement with the condition that it describes.
Note that "rate" refers to initial velocity Vo where steady state conditions are assumed. [Etotal] refers to the total enzyme
concentration and [Efree] refers to the concentration of free enzyme.
[S] << Km
[ES] is much lower than [Efree].
The rate is directly proportional to [S].
[S] = Km
[Efree] is equal to [ES].
[S] >> Km
Almost all active sites will
be filled.
Adding more S will not increase
the rate.
Answer Bank
Not true for any of these
conditions
Increasing [Etotal] will lower Km.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F2721ccf2-fbe1-4868-87fa-588e33d78a8e%2F8a4cddee-1f18-4d19-a4c6-697d0b171a33%2Fske0l7_processed.png&w=3840&q=75)
Transcribed Image Text:The Michaelis-Menten equation models the hyperbolic relationship between [S] and the initial reaction rate V₁ for an
enzyme-catalyzed, single-substrate reaction E + S ⇒ ES →→ E + P. The model can be more readily understood when
comparing three conditions: [S] << Km, [S] = Km, and [S] >> Km.
Match each statement with the condition that it describes.
Note that "rate" refers to initial velocity Vo where steady state conditions are assumed. [Etotal] refers to the total enzyme
concentration and [Efree] refers to the concentration of free enzyme.
[S] << Km
[ES] is much lower than [Efree].
The rate is directly proportional to [S].
[S] = Km
[Efree] is equal to [ES].
[S] >> Km
Almost all active sites will
be filled.
Adding more S will not increase
the rate.
Answer Bank
Not true for any of these
conditions
Increasing [Etotal] will lower Km.
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