[S] << Km [S] = = Km [S] >> Km Not true for any of these conditions Almost all active sites are empty. [ES] is much higher than [Efree]. [Efree] is equal to [ES]. Reaction rate is independent of [S. [Efree] is about equal to [Etotai]- Increasing [Etotal] will lower Km-
[S] << Km [S] = = Km [S] >> Km Not true for any of these conditions Almost all active sites are empty. [ES] is much higher than [Efree]. [Efree] is equal to [ES]. Reaction rate is independent of [S. [Efree] is about equal to [Etotai]- Increasing [Etotal] will lower Km-
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
Related questions
Question
The Michaelis‑Menten equation models the hyperbolic relationship between [S] and the initial reaction rate ?0V0 for an enzyme‑catalyzed, single‑substrate reaction E+S↽−−⇀ES⟶E+PE+S↽−−⇀ES⟶E+P. The model can be more readily understood when comparing three conditions: [S]<<?m[S]<<Km, [S]=?m[S]=Km, and [S]>>?m[S]>>Km.
Match each statement with the condition that it describes.
Note that "rate" refers to initial velocity ?0V0 where steady state conditions are assumed. [Etotal][Etotal] refers to the total enzyme concentration and [Efree][Efree] refers to the concentration of free enzyme.
![[S] << Km
[S] = Km
[S] >> Km
Not true for any of these
conditions
Almost all active sites are empty.
[ES] is much higher than [Efree].
[Efree] is equal to [ES].
Reaction rate is independent of
[S.
[Efree] is about equal to [Etotal].
Increasing [Etotal] will lower Km-
Answer Bank
Incorrect](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F602d9d36-1a58-4410-9b5f-f8da28ce88a2%2F185bc702-e881-43eb-832e-7d5e1add3336%2Fncis0mcp_processed.png&w=3840&q=75)
Transcribed Image Text:[S] << Km
[S] = Km
[S] >> Km
Not true for any of these
conditions
Almost all active sites are empty.
[ES] is much higher than [Efree].
[Efree] is equal to [ES].
Reaction rate is independent of
[S.
[Efree] is about equal to [Etotal].
Increasing [Etotal] will lower Km-
Answer Bank
Incorrect
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