The contraction of cardiac muscle cells results from the increase in Ca?+ levels in the cytosol. For these cells to relax, an antiport removes Ca?+ from the cytosol for every Na* that is taken in. Digitalis is a drug that is used to make the heart contract more strongly. This drug partially inhibits the Na*-K* ATPase in the cardiac cells. Applying the concepts from membrane transport, answer the following: a. Propose an explanation for the drug's effect. b. What will likely happen if too much of the drug is taken in? Why do you say so?
The contraction of cardiac muscle cells results from the increase in Ca?+ levels in the cytosol. For these cells to relax, an antiport removes Ca?+ from the cytosol for every Na* that is taken in. Digitalis is a drug that is used to make the heart contract more strongly. This drug partially inhibits the Na*-K* ATPase in the cardiac cells. Applying the concepts from membrane transport, answer the following: a. Propose an explanation for the drug's effect. b. What will likely happen if too much of the drug is taken in? Why do you say so?
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Transcribed Image Text:The contraction of cardiac muscle cells results from the increase in Ca?+ levels in the cytosol. For these
cells to relax, an antiport removes Ca?+ from the cytosol for every Nat that is taken in. Digitalis is a
drug that is used to make the heart contract more strongly. This drug partially inhibits the Na*-K*
ATPase in the cardiac cells. Applying the concepts from membrane transport, answer the following:
a. Propose an explanation for the drug's effect.
b. What will likely happen if too much of the drug is taken in? Why do you say so?
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