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- Give the major products or reagents represented by letters A and B:Treatment of W with CH3Li, followed by CH3I, affords compound Y (C7H14O) as the major product. Y shows a strong absorption in its IR spectrum at 1713 cm−1, and its 1H NMR spectrum is given below. (a) Propose a structure for Y. (b) Draw a stepwise mechanism for the conversion of W to Y.Draw the products (including the stereochemistry) formed in the following reaction.
- 2) How would you synthesize the following compounds from cyclohexanone? CH₂Br CH₂C6H5 A Br B C D CH2CH2CO2HReaction of benzylmagnesium chloride with formaldehyde yieldsalcohols N and P after protonation. Draw a stepwise mechanism thatshows how both products are formedA step in a synthesis of PGE1 (prostaglandin E1, alprostadil) is the reaction of a trisubstituted cyclohexene with bromine to form a bromolactone. Propose a mechanism for formation of this bromolactone and account for the observed stereochemistry of each substituent on the cyclohexane ring. Alprostadil is used as a temporary therapy for infants born with congenital heart defects that restrict pulmonary blood flow. It brings about dilation of the ductus arteriosus, which in turn increases blood flow in the lungs and blood oxygenation.
- Identify the missing reagents a-f in the following scheme:What carbonylPart A compound and what phosphonium ylide are needed to synthesize the following compound Part A C CH=CHCH,CH,CH,Which of the following pairs of compounds are keto-enol tautomers? ОН (a) and H. II ОН ОН (b) and I II ОН (c) CH and CH I II