a) 1) The following reaction will not work as written. How can the scientist change this reaction to form the desired product as the major product? (CH3)2Cu-Li+, then H3O+ OH a Use H3CMgBr rather than (CH3)2Cu-Li+ as the first step of the reaction b. Add 2 equivalents of (CH3)2Cu-Li+ C. Use ethanol in the second step rather than hydronium ion d. Protect the ketone before adding (CH3)2Cu-Li+ 2) What is the major product of the following reaction? 0 1. NaOCH3 ? 2. H3O+ OCH3 alls o ge авто d) of a) 1) The following reaction will not work as written. How can the scientist change this reaction to form the desired product as the major product? (CH3)2Cu-Li+, then H3O+ OH a Use H3CMgBr rather than (CH3)2Cu-Li+ as the first step of the reaction b. Add 2 equivalents of (CH3)2Cu-Li+ C. Use ethanol in the second step rather than hydronium ion d. Protect the ketone before adding (CH3)2Cu-Li+ 2) What is the major product of the following reaction? 0 1. NaOCH3 ? 2. H3O+ OCH3 alls o ge авто d) of

Organic Chemistry
9th Edition
ISBN:9781305080485
Author:John E. McMurry
Publisher:John E. McMurry
Chapter10: Organohalides
Section10.SE: Something Extra
Problem 45AP
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a)
1) The following reaction will not work as written. How can the scientist change this reaction to
form the desired product as the major product?
(CH3)2Cu-Li+, then H3O+
OH
a
Use H3CMgBr rather than (CH3)2Cu-Li+ as the first step of the reaction
b. Add 2 equivalents of (CH3)2Cu-Li+
C.
Use ethanol in the second step rather than hydronium ion
d. Protect the ketone before adding (CH3)2Cu-Li+
2) What is the major product of the following reaction?
0
1. NaOCH3
?
2. H3O+
OCH3
alls o ge
авто
d)
of
Transcribed Image Text:a) 1) The following reaction will not work as written. How can the scientist change this reaction to form the desired product as the major product? (CH3)2Cu-Li+, then H3O+ OH a Use H3CMgBr rather than (CH3)2Cu-Li+ as the first step of the reaction b. Add 2 equivalents of (CH3)2Cu-Li+ C. Use ethanol in the second step rather than hydronium ion d. Protect the ketone before adding (CH3)2Cu-Li+ 2) What is the major product of the following reaction? 0 1. NaOCH3 ? 2. H3O+ OCH3 alls o ge авто d) of
a)
1) The following reaction will not work as written. How can the scientist change this reaction to
form the desired product as the major product?
(CH3)2Cu-Li+, then H3O+
OH
a
Use H3CMgBr rather than (CH3)2Cu-Li+ as the first step of the reaction
b. Add 2 equivalents of (CH3)2Cu-Li+
C.
Use ethanol in the second step rather than hydronium ion
d. Protect the ketone before adding (CH3)2Cu-Li+
2) What is the major product of the following reaction?
0
1. NaOCH3
?
2. H3O+
OCH3
alls o ge
авто
d)
of
Transcribed Image Text:a) 1) The following reaction will not work as written. How can the scientist change this reaction to form the desired product as the major product? (CH3)2Cu-Li+, then H3O+ OH a Use H3CMgBr rather than (CH3)2Cu-Li+ as the first step of the reaction b. Add 2 equivalents of (CH3)2Cu-Li+ C. Use ethanol in the second step rather than hydronium ion d. Protect the ketone before adding (CH3)2Cu-Li+ 2) What is the major product of the following reaction? 0 1. NaOCH3 ? 2. H3O+ OCH3 alls o ge авто d) of
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