Specificity Specificity is the ability to measure accurately and specifically the analyte of interest in the presence of other components that may be expected to be present in the sample matrix. It is a measure of the degree of interference from such components, as other active ingredients, excipients, impurities, and degradation products, insuring that a peak response is due to a single component only. Experimental Dissolve amount of paracetamol (20 µg/ml) powder in three different volumetric flasks containing IN HCI, IN NaOH and 6% H₂O2 respectively, then keep your solution overnight in a fume hood. Analysis your solution by injecting three times each solution and calculates the recovery%

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Specificity
Specificity is the ability to measure accurately and specifically the analyte of interest in the
presence of other components that may be expected to be present in the sample matrix. It is a
measure of the degree of interference from such components, as other active ingredients,
excipients, impurities, and degradation products, insuring that a peak response is due to a single
component only.
Experimental
Dissolve amount of paracetamol (20 µg/ml) powder in three different volumetric
flasks containing IN HCI, IN NaOH and 6% H₂O2 respectively, then keep your
solution overnight in a fume hood. Analysis your solution by injecting three times
each solution and calculates the recovery%
1 N HCI
Peak area
Actual exp. conc.
Recovery%
IN NaOH
6% H₂O2
Transcribed Image Text:Specificity Specificity is the ability to measure accurately and specifically the analyte of interest in the presence of other components that may be expected to be present in the sample matrix. It is a measure of the degree of interference from such components, as other active ingredients, excipients, impurities, and degradation products, insuring that a peak response is due to a single component only. Experimental Dissolve amount of paracetamol (20 µg/ml) powder in three different volumetric flasks containing IN HCI, IN NaOH and 6% H₂O2 respectively, then keep your solution overnight in a fume hood. Analysis your solution by injecting three times each solution and calculates the recovery% 1 N HCI Peak area Actual exp. conc. Recovery% IN NaOH 6% H₂O2
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