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What types of problem will occurs if excipients are not use during formulation of suspension?
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- Identify the neutral polymer carrier particle used together with iodine for antiseptic use.Consider the following from the Ampicillin for Injection, USP package insert: For Intramuscular Use: Label Claim 250mg 500mg 1g 2g Amount of Diluent (mL) Approx. Volume (ml) 0.9 1.7 3.4 6.8 1 2 4 8 a) What is the amount of diluent needed to reconstitute a 1 g vial? b) What is the powder volume for a 1 g vial of ampicillin? Approx. Concentration (mg/mL) 250 250 250 250 Later in the package insert you see: For Direct Intravenous Use: Add 5 mL Sterile Water for Injection or Bacteriostatic Water for Injection to the 250 and 500 mg vials and administer slowly over a 3 to 5-minute period. Ampicillin for Injection, 1 g or 2 g, may also be given by direct intravenous administration. Dissolve in 7.4 or 14.8 mL Sterile Water for Injection or Bacteriostatic Water for Injection, respectively, and administer slowly over at least 10 to 15 minutes. c) What is the amount of diluent needed to reconstitute a 1 g vial of ampicillin for direct IV injection d) What is the total amount of volume that will…Order: Phenytoin (Dilantin) 150mg p.o. t.i.d. Available on hand: Phenytoin (Dilantin) 125mg/4ml. How many ml to be given?
- The reason why most antibiotics as oral suspension dosage forms are commercially available as dry powders, to be reconstituted with water just prior to dispensing, is:A doctor had ordered 1 floz 4% medication syrup bid X 5d. How many floz are required in total? How many floz of each of two syrups that are 2% medication and 7% should be mixed to produce the 4% medication syrup?What will happen if there are inconsistencies on the tablet diameter and thickness of a product batch?
- Give explanation of correct option and explanation of incorrect options. Hand written solutions are strictly prohibited.Doris has reconstituted a bottle of Cefprozil® Oral Suspension to fill a patient's prescription. The prescription calls for 400 mg CefprozilⓇq12h for 7 days. Doris needs to know if the amount of reconstituted medication in the bottle will be enough to last the patient for 7 days. Calculate the total amount of medication in the bottle after this medication has been reconstituted: TEVA Seferle, PA 18960 PHARMACEUTICALS USA SHAKE WELL BEFORE USING KEEP THIS AND ALL MEDICATIONS OUT OF THE REACH OF CHILDREN 5 mL (approx. one teaspoonful) of suspension. Phenylketonurics: This product contains 10.1 mg of phenylalanine per Store constituted suspension in refrigerator. Discard after 14 days Ruv. A 7/2005 L52974 NDC 0093-1075-78 CEFPROZIL for Oral Suspension USP 125 mg/5 mL* Each 5 mL, when constituted according to directions, contains 125 mg anhydrous cetprozil, Ronly 75 mL (when mixed) TEVA To the Pharmacist: Prepare suspension at time of dispensing. Add to the bottle a total of 59 ml water.…Give one advantage and one disadvantage of pharmaceutical solid dosage forms. Explain each advantage and disadvantage thoroughly.
- What are the advantages of granulation ? during tablet formulation. DefineGive the drug examples of emulsion prepare by these method:- 1)dry gum method 2)wet gum method 3)bottle gum methodTRUE OR FALSE Properties of a drug suitable for transdermal use include: High molecular mass Low lipophilicity Low required daily dose Low potency High partition coefficient Problems with opioid TDDS include: Poor patient compliance Allergy Constipation Respiratory depression Cognitive dysfunction