You receive a prescription for Epanutin® Suspension. The patient normally takes 150mg daily in capsule form, however he has recently started to have difficulty in swallowing them. The doctor asks you to check that the Epanutin® Capsules and Suspension are equivalent to each other. The following information is extracted from the BNF. Dose equivalence and conversion Preparations containing phenytoin sodium are not bioequivalent to those containing phenytoin base (such as Epanutin® suspension); 100 mg of phenytoin sodium is approximately equivalent in therapeutic effect to 92 mg phenytoin base. Epanutin 30mg/5ml oral suspension (Pfizer Ltd) Phenytoin 6 mg per 1 ml Phenytoin sodium 100mg capsules (Actavis UK Ltd) Phenytoin sodium 100 mg What daily dose of Epanutin® Suspension should be written on the dispensing label (in ml)? (Round to the nearest ml)
You receive a prescription for Epanutin® Suspension. The patient normally takes 150mg daily in capsule form, however he has recently started to have difficulty in swallowing them. The doctor asks you to check that the Epanutin® Capsules and Suspension are equivalent to each other. The following information is extracted from the BNF.
Dose equivalence and conversion
Preparations containing phenytoin sodium are not bioequivalent to those containing phenytoin base (such as Epanutin® suspension); 100 mg of phenytoin sodium is approximately equivalent in therapeutic effect to 92 mg phenytoin base.
Epanutin 30mg/5ml oral suspension (Pfizer Ltd)
Phenytoin 6 mg per 1 ml
Phenytoin sodium 100mg capsules (Actavis UK Ltd)
Phenytoin sodium 100 mg
What daily dose of Epanutin® Suspension should be written on the dispensing label (in ml)? (Round to the nearest ml)
units -ml
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