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Curren'S Math For Meds: Dosages & Sol

Curren'S Math For Meds: Dosages & Sol

11th Edition

ISBN:9781305143531

Author:CURREN

Publisher:CURREN

Chapter10: Reconstitution Of Powdered Drugs

Section: Chapter Questions

Problem 38SST

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Question

What is the experimentally-determined minimum inhibitory concentration of the antibiotic being
tested in this picture, based on the results shown in the picture?
0.06 0.125 0.25
1.0 μg/ml
8.0 µg/ml
0.5 µg/ml
○ 0.06 µg/ml
µg/ml
0.5
1.0 2.0 4.0
8.0

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Which of the following tubes represent the minimum inhibitory concentration of the antibiotic tested? * B C D 2 4 8 16 µg/mL µg/mL µg/mL ug/mL Tube A at 2 µg/mL Tube B at 4 µg/mL Tube C at 8 µg/mL O Tube D at 16 µg/mL A,
A 250 mL IV solution contains 25,000 units of heparin. The desired dosage is 8 units/kg/hr. The patient weighs 220 Ibs. The drop factor is 60 gtts/mL.. How many units of heparin are in 5 mL of solution? (Hint: how many are in 1 mL? Now, how many are in 5?)
From the following data, find the % (w/w) cream of tartar (KHC4H406, MM=188): Wt of sample = 1.4160 g NaOH titrant used = 20.87 mL HCI used for back titration = 1.27 mL 1.00 mL HCI 1.12 mL NaOH 1.00 mL HCI A 0.01930 g CaCO3 89.08% (w/w) 87.12% (w/w) O 47.75% (w/w) O 95.59% (W/w)
Based on the following image, which concentration of antibiotic would be considered the minimum bactericidal concentration (MBC)? a. 8 ug/mlb. 16 ug/mlc. 25 ug/ml
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You have an order for 1 gram of Cefazolin in D5W 100 ml. You have added 5 ml of sterile water to the 1 gram vial to reconstitute powder. However the recommended manufacturer’s diluent amount is 10 ml of sterile water for a final concentration of 100 mg/ml. How would reconstituting the vial with 5 mls affect the concentration and the final calculated dose?
A patient received a single 245.97 mg IV bolus dose of an antibiotic and the plasma drug concentration was determined as 13.62 mg/L and 5.94 mg/L at 2.04 hours and 11.52 hours following the drug administration, respectively. On a separate occasion, a single 427.73 mg oral dose of the same antibiotic was administered to the same patient and the plasma drug concentration was determined as 0, 5.01, 5.77, 3.43, 1.1 mg/L at 0, 3.15, 7.69, 14.39, and 27.5 hours following the drug administration. Please calculate the bioavailability of this drug without utilizing any data fitting program.
The order reads: Give mannitol 0.5 g/kg IV now, over 2 hours. The patient weighs 165 lb, and you have a 100-mL vial of 20% mannitol. How many grams will the patient receive? How many milliliters of mannitol will you prepare for this infusion?
Phenylephrine and nafazolin solutions are used as decongestants to relieve nasal congestion. Your patient has been given the following prescription below. You need to prepare 100 g of this nasal spray and make it isotonic. 1. There is an available 25% w/w Phenylephrine solution in the pharmacy. How many g of this solution will you need to supply the needed 0.5% of the patient? A. 1.0 g В. 1.5 g С. 2.0 g D. 4.0 g 2. Given the amount calculated on the previous item, and if the E value of phenylephrine HCl is 0.32, calculate its corresponding sodium chloride tonicic equivalent. А. 0.16 B. 0.64 С. 1.60 D. 6.40 3. If the E value of nafazolin is 0.27, what is the sodium chloride tonicic equivalent of the patient's needed nafazolin? A. 0.0135 B. 0.1350 1.3500 D. 13.500 4. What is the combined sodium chloride tonicic equivalent of the remaining ingredients (edetate disodium (E =0.24) and sodium metabisulfite (E = 0.7)? A. 1.060 B. 0.106 С. 1.290 D. 0.129 5. To make the solution isotonic, what…
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A medication order for a patient weighing 70 Kg is 0.75 mg of ampicillin per Kg BW to be added to 900 mL of 5% dextrose injection. The ampicillin injection is to be obtained in 2.5 mg/mL ampule. What is the total volume in mL of the IV admixture? Choose the best answer.
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