A pharmacist is preparing a compounded oral suspension preparation using commercially available tablets as the source of the active pharmaceutical ingredient (API). The recipe is as follows: "API" 0.8 mg/mL Structured suspension vehicle qs ad 240 mL Sig: 1 tsp PO BID PRN The tablets are available at a strength of 20 mg. Assume that when the the minimum number of tablets is used to prepare this compounded suspension, the crushed tablets take up 12.2 mL of volume.What volume of suspension structured vehicle will be needed to prepare this compounded oral solution?Round the answer to one decimal place.

A pharmacist is preparing a compounded oral suspension preparation using commercially available tablets as the source of the active pharmaceutical ingredient (API). The recipe is as follows: "API" 0.8 mg/mL Structured suspension vehicle qs ad 240 mL Sig: 1 tsp PO BID PRN The tablets are available at a strength of 20 mg. Assume that when the the minimum number of tablets is used to prepare this compounded suspension, the crushed tablets take up 12.2 mL of volume.What volume of suspension structured vehicle will be needed to prepare this compounded oral solution?Round the answer to one decimal place.

Curren'S Math For Meds: Dosages & Sol

11th Edition

ISBN:9781305143531

Author:CURREN

Publisher:CURREN

Chapter6: Oral Medication Labels And Dosage Calculation

Section: Chapter Questions

Problem 6.9P

See similar textbooks

Similar questions

A pharmacist is preparing a compounded oral suspension preparation using commercially available tablets as the source of the active pharmaceutical ingredient (API). The recipe is as follows: "API" 0.9 mg/mL Structured suspension vehicle qs ad 150 mL Sig: 2 tsp PO QD x14 day The tablets are available at a strength of 25 mg. What is the minimum number of tablets needed to prepare this compounded suspension? Round your answer up to the number of whole tablets to use.
Granisetron HCl is indicated for the prevention of nausea and vomiting associated with chemotherapy and radiotherapy. Your 90 kg has been prescribed granisetron HCl at the dose recommended on the drug label below. Determine what volume of this medication you will administer at each dose. Indicate the quantity and unit of measure where specified. Quantity: Unit:
The drug dosage for the patient is calculated using a BSA of 1.9m2. If the order is 15mg per m2, how many milligrams is the desired dose?
a) The total amount excreted into urine as unchanged drug after an oral tablet (A) of 50 mg was 36.4 mg. After an oral capsule dose (B) of 25 mg the Uo was 20.3 mg. Calculate the relative bioavailability of the tablet A with respect to capsule B. If the absolute bioavailability of the oral capsule is determined to be 0.86 calculate the absolute bioavailability of the tablet dosage form. You are required to list the given data, formula and steps for calculations
Amoxicillin/clavulanate potassium (AUGMENTIN) powder for oral suspension is prepared prior to dispensing by adding 134 mL of purified water to the contents of the container to prepare 150 mL of suspension. If each teaspoonful of suspension contains 125 mg of amoxicillin and 31.25 mg of clavulanate potassium, how much of each of these agents is contained in the dry powder prior to reconstitution
A 5% dextrose in 1/2 normal saline (D5 1/2 NS) solution is commonly administered to patients needing post-operative IV fluids. How could you prepare 500 mL of this solution? Dextrose is 5% (m/v) and the NaCl is 0.45% (m/v).
Consider the following from the Ampicillin for Injection, USP package insert: For Intramuscular Use: Label Claim 250mg 500mg 1g 2g Amount of Diluent (mL) Approx. Volume (ml) 0.9 1.7 3.4 6.8 1 2 4 8 a) What is the amount of diluent needed to reconstitute a 1 g vial? b) What is the powder volume for a 1 g vial of ampicillin? Approx. Concentration (mg/mL) 250 250 250 250 Later in the package insert you see: For Direct Intravenous Use: Add 5 mL Sterile Water for Injection or Bacteriostatic Water for Injection to the 250 and 500 mg vials and administer slowly over a 3 to 5-minute period. Ampicillin for Injection, 1 g or 2 g, may also be given by direct intravenous administration. Dissolve in 7.4 or 14.8 mL Sterile Water for Injection or Bacteriostatic Water for Injection, respectively, and administer slowly over at least 10 to 15 minutes. c) What is the amount of diluent needed to reconstitute a 1 g vial of ampicillin for direct IV injection d) What is the total amount of volume that will…
A nurse wants to know the what volume of Water for Injection, BP to be added to a vial containing 500mg doxorubicin to produce an injection with a concentration of 2.5 mg/mL. The displacement volume of doxorubicin is 0.3 mL/10 mg.
Both the physical properties of the API and the excipients are essential to ensure that the formulation is physically stable and suitable for administration to patients. Discuss the general formulation considerations. The instability of emulsions may be either reversible or irreversible. Cracking indicates the extensive coalescence of the internal phase, consequently, leads to the separation of the emulsion into two distinct layers. How the cracking is occurring in the emulsions? If an emulsion has cracked will it be recovered. If yes/no discuss the phenomena. Discuss the lyophilization and appraise its importance in the pharmaceutical industry with suitable examples
The cost of each vial of the drug ‘A’ is $450.50 dollar where it contains 30 mg. The usual dose of drugadministered is 145 mg once every 2 weeks, during a 12-week period to a patient weighing 190 lb and aheight of 6 ft 2 inch.d) Calculate the cost for the full treatment for the above patient.
What is the minimum volume of dissolution media required to provide sink condition in dissolution test of a tablet dosage form (its weight: 1350 mg; dose strength: 1000 mg) regarding the following conditions? The molecular weight of an active drug substance is 500 Da; the dissolution media is water and the solubility of active drug substance in water is 10 mg/Ml (4. SLAYT) 500 ml 1000 ml 1350 ml 100 ml 135 ml
Please show dimensional analysis to solve