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[S] << Km [S] = Km [S] >> Km Not true for any of these conditions

[S] << Km [S] = Km [S] >> Km Not true for any of these conditions

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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The Michaelis-Menten equation models the hyperbolic relationship between [S] and the initial reaction rate V for an enzyme-catalyzed, single-substrate reaction E + SES →E + P. The model can be more readily understood when comparing three conditions: [S] << Km. [S] = Km, and [S] >> Km. Match each statement with the condition that it describes. Note that "rate" refers to initial velocity V, where steady state conditions are assumed. [Etotal] refers to the total enzyme concentration and [Efree] refers to the concentration of free enzyme. [S] << Km Increasing [Ewall will increase Km. Almost all active sites are empty. [S] = Km Answer Bank [Enel is about equal to [Exotal]. [ES] is much higher than [Efree] [S] >> Km Reaction rate is independent of [S]. Not true for any of these conditions The rate is half of the maximum rate.
Transcribed Image Text:The Michaelis-Menten equation models the hyperbolic relationship between [S] and the initial reaction rate V for an enzyme-catalyzed, single-substrate reaction E + SES →E + P. The model can be more readily understood when comparing three conditions: [S] << Km. [S] = Km, and [S] >> Km. Match each statement with the condition that it describes. Note that "rate" refers to initial velocity V, where steady state conditions are assumed. [Etotal] refers to the total enzyme concentration and [Efree] refers to the concentration of free enzyme. [S] << Km Increasing [Ewall will increase Km. Almost all active sites are empty. [S] = Km Answer Bank [Enel is about equal to [Exotal]. [ES] is much higher than [Efree] [S] >> Km Reaction rate is independent of [S]. Not true for any of these conditions The rate is half of the maximum rate.
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