▲ [S] = 0.2 mM "[S] = 0.4 mM I/Vav 8 9 5 y=0.01357x+3.6976 3 y=0.0795x+2.7693 2 1 -30 -20 -10 0 10 20 30 [I](M) Mixed inhibition, Ki= -21.2 UM ○ Mixed inhibition, Ki= 1/16.5 uM Competitive inhibition, Ki= 16.5 UM ○ Competitive inhibition, Ki= -1/16.5 UM None of the above
▲ [S] = 0.2 mM "[S] = 0.4 mM I/Vav 8 9 5 y=0.01357x+3.6976 3 y=0.0795x+2.7693 2 1 -30 -20 -10 0 10 20 30 [I](M) Mixed inhibition, Ki= -21.2 UM ○ Mixed inhibition, Ki= 1/16.5 uM Competitive inhibition, Ki= 16.5 UM ○ Competitive inhibition, Ki= -1/16.5 UM None of the above
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
Related questions
Question
Following is a Dixon plot for PNPP inhibition by inorganic phosphates. What answer choice shows the correct combination of the mode of inhibition and Ki of the EI complex?
- Mixed inhibition, Ki= -21.2 uM
- Mixed inhibition, Ki= 1/16.5 uM
- Competitive inhibition, Ki= 16.5 uM
- Competitive inhibition , Ki= -1/16.5 uM
- None of the above
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