rostaglandins are a group of lipid compounds having diverse hormone-like activities in animals. They are biosynthesized from the fatty acid arachidonic acid, catalyzed by the enzyme cyclooxygenase. The biosynthesis involves via a multistep radical mechanism. Can u show me in a stepwise mechanism how it is converted from radical intermediate A to prostaglandin PGG2.

Biochemistry
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ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
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Chapter1: Biochemistry: An Evolving Science
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Prostaglandins are a group of lipid compounds having diverse hormone-like activities in animals. They are biosynthesized from the fatty acid arachidonic acid, catalyzed by the enzyme cyclooxygenase. The biosynthesis involves via a multistep radical mechanism. Can u show me in a stepwise mechanism how it is converted from radical intermediate A to prostaglandin PGG2.

.CO,H
.CO2H
H
Me
Me
cyclooxygenase
A
arachidonic acid
CO2H
CSH11
ÕOH
PGG2
Transcribed Image Text:.CO,H .CO2H H Me Me cyclooxygenase A arachidonic acid CO2H CSH11 ÕOH PGG2
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