rise in the intracellular Ca2+ concentration causes muscle cells to contract. In addition to an ATPdriven Ca2+-pump, heart muscle cells, which contract quickly and regularly, have an antiporter that exchanges Ca2+ for extracellular Na+ across the plasma membrane. This antiporter rapidly pumps most of the entering Ca2+ ions back out of the cell, allowing the cell to relax. Ouabain, a drug that is used in the treatment of patient with heart disease, make the heart contract more strongly. The drug functions by partially inhibiting the Na+-K+ pump in the membrane of the heart muscle cell. What will happen if too much of the drug is taken?
rise in the intracellular Ca2+ concentration causes muscle cells to contract. In addition to an ATPdriven Ca2+-pump, heart muscle cells, which contract quickly and regularly, have an antiporter that exchanges Ca2+ for extracellular Na+ across the plasma membrane. This antiporter rapidly pumps most of the entering Ca2+ ions back out of the cell, allowing the cell to relax. Ouabain, a drug that is used in the treatment of patient with heart disease, make the heart contract more strongly. The drug functions by partially inhibiting the Na+-K+ pump in the membrane of the heart muscle cell. What will happen if too much of the drug is taken?
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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A rise in the intracellular Ca2+ concentration causes muscle cells to contract. In addition to an ATPdriven Ca2+-pump, heart muscle cells, which contract quickly and regularly, have an antiporter that
exchanges Ca2+ for extracellular Na+ across the plasma membrane. This antiporter rapidly pumps most
of the entering Ca2+ ions back out of the cell, allowing the cell to relax. Ouabain, a drug that is used in
the treatment of patient with heart disease, make the heart contract more strongly. The drug functions by
partially inhibiting the Na+-K+ pump in the membrane of the heart muscle cell.
What will happen if too much of the drug is taken?
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