raw OUT THE arrow pushing reaction mechanism for the following steps of glycolysis: SHOW/IDENTIFY the arrow pushing mechanism in at least 2 steps. CH,OPO CH2OH H H H H hexokinase 2+ Mg H ОН + ATP ОН + ADP + H* H OH Но ОН H. OH H OH Glucose-6-phosphate (G6P) Glucose

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**Title: Understanding the Arrow Pushing Mechanism in Glycolysis**

In this section, we will explore the arrow pushing reaction mechanism of glycolysis, specifically for the initial stages involving glucose transformation into glucose-6-phosphate (G6P).

**Reaction Overview:**

1. **Substrates and Enzyme:**
   - **Glucose**: The starting molecule, depicted as a hexagonal carbon ring with hydroxyl (OH) groups and a CH2OH side group.
   - **ATP (Adenosine Triphosphate)**: Serves as the phosphate donor.
   - **Hexokinase**: An enzyme that catalyzes the phosphorylation of glucose in the presence of Mg²⁺ ions.

2. **Products:**
   - **Glucose-6-phosphate (G6P)**: The phosphorylated form of glucose, containing an OPO₃²⁻ group replacing a hydroxyl group.
   - **ADP (Adenosine Diphosphate)**
   - **H⁺ (Proton)**

**Reaction Mechanism:**

- In this reaction, the hydroxyl group on the 6th carbon of glucose interacts with the phosphate group from ATP.
- The reaction is facilitated by hexokinase in the presence of Mg²⁺ ions.
- The ATP molecule transfers a phosphate group to the glucose, forming glucose-6-phosphate (G6P) and converting ATP into ADP.

By understanding the detailed mechanism and the role of hexokinase, one can appreciate the fundamental biochemical process crucial in energy production within cells.
Transcribed Image Text:**Title: Understanding the Arrow Pushing Mechanism in Glycolysis** In this section, we will explore the arrow pushing reaction mechanism of glycolysis, specifically for the initial stages involving glucose transformation into glucose-6-phosphate (G6P). **Reaction Overview:** 1. **Substrates and Enzyme:** - **Glucose**: The starting molecule, depicted as a hexagonal carbon ring with hydroxyl (OH) groups and a CH2OH side group. - **ATP (Adenosine Triphosphate)**: Serves as the phosphate donor. - **Hexokinase**: An enzyme that catalyzes the phosphorylation of glucose in the presence of Mg²⁺ ions. 2. **Products:** - **Glucose-6-phosphate (G6P)**: The phosphorylated form of glucose, containing an OPO₃²⁻ group replacing a hydroxyl group. - **ADP (Adenosine Diphosphate)** - **H⁺ (Proton)** **Reaction Mechanism:** - In this reaction, the hydroxyl group on the 6th carbon of glucose interacts with the phosphate group from ATP. - The reaction is facilitated by hexokinase in the presence of Mg²⁺ ions. - The ATP molecule transfers a phosphate group to the glucose, forming glucose-6-phosphate (G6P) and converting ATP into ADP. By understanding the detailed mechanism and the role of hexokinase, one can appreciate the fundamental biochemical process crucial in energy production within cells.
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