Question 2: Consider the following pedigree, which traces the inheritance of a single-gene hereditary disease. Only individuals that are either affected or normal are shown. In other words, potential heterozygotes are NOT indicated. Assume that there is complete penetrance and no variable expressivity, and no new mutations. I II 5 IV Characterize each of the following modes of inheritance as impossible or possible. Justify your answers. Autosomal recessive b. Autosomal dominant C. X-linked recessive X-linked dominant Y-linked Sex-limited Sex influenced, dominant in males Sex influenced, dominant in females d. e £. 2 h. i. Mitochondrial inheritance

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Inheritance and Mendelian Genetics

Inheritance means the passing of traits to offspring from parents. These traits could be passed either through asexual reproduction or sexual reproduction. The offspring receives the genetic material from the parents. Mendelian inheritance is a certain biological inheritance that follows the rules and principles laid down by Gregor Mendel in 1865. The initial hypothesis was considered wrong, but other inheritance theories modified the concept of inheritance and thus genetics.