Question 1: Look at the following normal and mutant DNA sequences. Normal Sequence (5'-3'): ATG AAC GTT ATC GCA Mutated Sequence (5'-3'): ATG AAT GTC ATC GCA a) What type of mutation has occurred (be specific)? b) Fill in the table for the normal and mutated sequences. Starting with the given 5'-3' sequence, input the complementary DNA, transcribed RNA from the 3'-5' DNA and translated polypeptide sequence for both. Hint: use the codon table! Normal sequence Mutant sequence DNA 5'-3' (given) DNA 3'-5' RNA Polypeptide (use 3 letter codes) c) Based on parts A and B above, what is the ultimate effect this mutation has had on the polypeptide? (1 sentence summary)

Human Anatomy & Physiology (11th Edition)
11th Edition
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Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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Question 1: Look at the following normal and mutant DNA sequences.
Normal Sequence (5'-3'): ATG AAC GTT ATC GCA
Mutated Sequence (5'-3'): ATG AAT GTC ATC GCA
a) What type of mutation has occurred (be specific)?
b) Fill in the table for the normal and mutated sequences. Starting with the given 5'-3'
sequence, input the complementary DNA, transcribed RNA from the 3'-5' DNA and
translated polypeptide sequence for both. Hint: use the codon table!
Normal sequence
Mutant sequence
DNA 5'-3'
(given)
DNA 3'-5'
RNA
Polypeptide
(use 3 letter
codes)
c) Based on parts A and B above, what is the ultimate effect this mutation has had on the
polypeptide? (1 sentence summary)
Transcribed Image Text:Question 1: Look at the following normal and mutant DNA sequences. Normal Sequence (5'-3'): ATG AAC GTT ATC GCA Mutated Sequence (5'-3'): ATG AAT GTC ATC GCA a) What type of mutation has occurred (be specific)? b) Fill in the table for the normal and mutated sequences. Starting with the given 5'-3' sequence, input the complementary DNA, transcribed RNA from the 3'-5' DNA and translated polypeptide sequence for both. Hint: use the codon table! Normal sequence Mutant sequence DNA 5'-3' (given) DNA 3'-5' RNA Polypeptide (use 3 letter codes) c) Based on parts A and B above, what is the ultimate effect this mutation has had on the polypeptide? (1 sentence summary)
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