Q5 Lactate dehydrogenase is one of the many enzymes that require NADH as coenzyme. It catalyzes the conversion of pyruvate to lactate: NADH + H* NAD C=0 НО —С—Н lactate dehydrogenase CH3 CH, Рyruvate L-Lactate Draw the mechanism of this reaction (show electron-pushing arrows). Show all structures and show the movement of electrons. (Hint: This is a common reaction throughout metabolism)

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
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Chapter1: Biochemistry: An Evolving Science
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Q5 Lactate dehydrogenase is one of the many enzymes that
require NADH as coenzyme. It catalyzes the conversion of
pyruvate to lactate:
NADH + H* NAD
C=0
НО -С—Н
lactate
dehydrogenase
CH3
CH3
Pyruvate
L-Lactate
Draw the mechanism of this reaction (show electron-pushing arrows).
Show all structures and show the movement of electrons. (Hint: This is a
common reaction throughout metabolism)
Transcribed Image Text:Q5 Lactate dehydrogenase is one of the many enzymes that require NADH as coenzyme. It catalyzes the conversion of pyruvate to lactate: NADH + H* NAD C=0 НО -С—Н lactate dehydrogenase CH3 CH3 Pyruvate L-Lactate Draw the mechanism of this reaction (show electron-pushing arrows). Show all structures and show the movement of electrons. (Hint: This is a common reaction throughout metabolism)
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