Predict the effect of each of the following mutants on the rate of glycolysis in liver cells (increase, decrease, no change): (a) Loss of the allosteric site for ATP in PFK-1 (b) Loss of the binding site for citrate in PFK-1 (c) Loss of the phosphatase domain of PFK-2/FBPase-2 (d) Loss of the binding site for fructose-1,6-bisphosphate in pyruvate kinase (e) Loss of acetyl-CoA binding site in pyruvate carboxylase

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A: Glycogen phosphorylase is the enzyme that breaks down glycogen to glucose-1 phosphate which is then…

Q: Fructose 2,6-bisphosphate allosterically [inhibits/activates] PFK-1 and allosterically…

A: The reactions that transform one molecule to another(reactants to products) within the living cells…

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A: Hi! As you have posted multiple questions, I will be answering the first question for you. If you…

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A: What is glycolysis Glycolysis Glycolysis is a ubiquitous catabolic pathway. Glycolysis is a pathway…

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A: “Since you have asked multiple question, we will solve the first question for you. If youwant any…

Q: Name three enzymes that are likely the source of bicarbonate ion that is involved with the formation…

A:

Q: a) Based on the mechanism shown in Figure 2A, what type of enzyme is transpeptidase? : Lyase…

A: Note : Hi ! Thank you for the question. We are authorized to answer three subparts at a time. Since…

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Q: (b)( ) In mature erythrocytes (red blood cells) the end product of glycolysis is lactate because of…

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Q: If the serine phoshorylated by Protein Kinase A (PKA) on phosphofructokinase-2 (PFK-2) were mutated…

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Q: Can you please explain this pathway on the slide?

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A: Multiple questions are asked.  I wil answer 1st question, as per guidelines   Novel competitive…

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Q: PFK-1 is actually a tetramer with four identical active sites that produced fructose…

A: PFK-1 Phosphofructokinase-1 or PFK-1 is an important regulatory enzymes of the process glycolysis.…

Metabolic pathways

Metabolism is defined as the group of life-supporting, enzyme-mediated chemical reactions in organisms. A metabolic pathway is a set of these chemical reactions that involve anabolism (synthesis of complex biomolecules) and catabolism (breakdown of biomolecules into small molecules) that occur inside a cell. Metabolites are the reacting substances, products, and intermediate substances of an enzymatic process that are altered by a series of chemical events catalyzed by enzymes.