Oogenesis
The formation of the ovum (mature female gamete) from undifferentiated germ cells is called oogenesis. This process takes place in the ovaries (female gonads). Oogenesis consists of three stages known as the multiplication phase, growth phase, and maturation phase.
Cell Division
Cell division involves the formation of new daughter cells from the parent cells. It is a part of the cell cycle that takes place in both prokaryotic and eukaryotic organisms. Cell division is required for three main reasons:
Prader-Willi syndrome and Angelman syndrome are both caused by deletion of a set of genes on
chromosome 15. The symptoms of Prader-Willi syndrome are short stature, small hands and
feet, hypotonia (floppiness), hypogonadism, mild mental retardation, and an uncontrollable
desire to eat (polyphagia). Angelman syndrome is characterized by an intellectual and
developmental delay, sleep disturbances, seizures, hand-flapping and other jerky movements,
frequent laughter or smiling, and usually a happy demeanor.
Please explain how the deletion of the same set of genes can result in such different diseases. In
your answer, be sure to discuss the role of genetic imprinting and epigenetics.
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