Phosphocreatine (G0ʹ = -43.1 kJ/mol) has a higher phosphoryl group transfer potential than ATP (G0ʹ = -30.5 kJ/mol). However, under certain physiological conditions, phosphoryl group is transferred from ATP to creatine. Explain this discrepancy.
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Phosphocreatine (G0ʹ = -43.1 kJ/mol) has a higher phosphoryl group transfer potential than ATP (G0ʹ = -30.5 kJ/mol). However, under certain physiological conditions, phosphoryl group is transferred from ATP to creatine. Explain this discrepancy.
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Many biochemical conversions are carried out via multi-step pathways although similar conversions can be done in an
organic chemistry lab in fewer steps. Explain why energetically it is reasonable to use multiple steps in biochemical conversions.
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What are isozymes? Humans contain several isozymes of hexokinase. Why does the body need several isozymes of hexokinase?
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1,3-bisphosphoglycerate is used to produce ATP. Which of the two phosphates of 1,3- bisphosphoglycerate is transferred to ADP to make ATP. Explain why it is this specific phosphate and not the other one.
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Triose phosphate isomerase is a diffusion-controlled enzyme. What reaction is catalyzed by this enzyme (structures of molecules not needed)? Explain why this enzyme has evolved to be a very fast enzyme
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