Pharmacokinetics is a branch of pharmacy wherein the rate of metabolism of a drug molecule is measured thereby allowing the prediction of drug levels in the body and addressing drug distribution problems. The table below shows the plasma concentration as a function of time for ceftriaxone, an antibiotic. Find the effective kinetic order for the time course of the drug concentration and the rate constant. Time, hr mg/L 1.0 137 6.0 120 12 103 24 76 48 42 72 23 96 12 144 3.7

Chemistry by OpenStax (2015-05-04)
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Author:Klaus Theopold, Richard H Langley, Paul Flowers, William R. Robinson, Mark Blaser
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Chapter12: Kinetics
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Problem 43E: Some bacteria are resistant to the antibiotic penicillin because they produce penicillinase, an...
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Find the effective kinetic order for the time course of the drug concentration and the rate constant.

Pharmacokinetics is a branch of pharmacy wherein the rate of metabolism of a drug molecule is
measured thereby allowing the prediction of drug levels in the body and addressing drug distribution
problems. The table below shows the plasma concentration as a function of time for ceftriaxone, an
antibiotic. Find the effective kinetic order for the time course of the drug concentration and the rate
constant.
Time, hr
mg/L
1.0
137
6.0
120
12
103
24
76
48
42
72
23
96
12
144
3.7
Transcribed Image Text:Pharmacokinetics is a branch of pharmacy wherein the rate of metabolism of a drug molecule is measured thereby allowing the prediction of drug levels in the body and addressing drug distribution problems. The table below shows the plasma concentration as a function of time for ceftriaxone, an antibiotic. Find the effective kinetic order for the time course of the drug concentration and the rate constant. Time, hr mg/L 1.0 137 6.0 120 12 103 24 76 48 42 72 23 96 12 144 3.7
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