Part III - Trait Analysis 1. The following pedigrees will be used to determine whether the trait is autosomal dominant or autosomal recessive. In tracing autosomal alleles, if both parents have the disorder and the offspring do not, the condition is autosomal dominant. If neither parent shows the disorder but some of their children do, the condition is autosomal recessive. A carrier is an individual who appears to be normal, but who is capable of passing on a gene for the disorder. If the characteristic is dominant, there can be no carriers because only a single gene is needed to show the disorder. Table Il provides some keys for your answers. Table II - Pedigree Keys Characteristic Autosomal Dominant Autosomal Recessive Figure IV - Pedigree 1 56 Key AA Affected Aa= Affected aa = Normal AA = Normal Aa= Carrier aa = Affected go Q8 - Is the gene for the condition autosomal dominant or recessive? Q9 - Identify the genotype for each individual using the above table. Use A_ if undetermined.

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Figure V - Pedigree 2
Q10 - Is the gene for the condition autosomal dominant or recessive?
Q11 - Identify the genotype for each individual using the above table. Use A_ if undetermined.
Part IV - The Blue People Of Troublesome Creek
Six generations after a French orphan named Martin Fugate settled on the banks of eastern
Kentucky's Troublesome Creek with his redheaded American bride, his great-great-great-great
grandson was born in a modern hospital not far from where the creek still runs. The boy inherited
his father's lankiness and his mother's slightly nasal way of speaking. What he got from Martin
Fugate was dark blue skin. "It was almost purple," his father recalls.
Doctors were so astonished by the colour of Benjy Stacy's skin that they raced him by ambulance
from the maternity ward in the hospital near Hazard to a medical clinic in Lexington. Two days of
tests produced no explanation for skin the colour of a bruised plum. A transfusion was being
prepared when Benjy's grandmother spoke up. "Have you ever heard of the blue Fugates of
Troublesome Creek?" she asked the doctors. "My grandmother Luna on my dad's side was a blue
Fugate. It was real bad in her," Alva Stacy, the boy's father, explained. The doctors finally came to
the conclusion that Benjy's colour was due to blood inherited from generations back.
Benjy lost his blue tint within a few weeks, and now he is about as normal looking a seven-year-old
boy as you could hope to find. His lips and fingernails still turn a shade of purple-blue when he gets
cold or angry, a quirk that so intrigued medical students after Benjy's birth that they would crowd
around the baby and try to make him cry. "Benjy was a pretty big item in the hospital," his mother
says with a grin. Dark blue lips and fingernails are the only traces of Martin Fugate's legacy left in the
boy; that, and the recessive gene that has shaded many of the Fugates and their kin blue for the past
162 years.
Given below is a pedigree of some of the blue people of Troublesome Creek
Transcribed Image Text:Figure V - Pedigree 2 Q10 - Is the gene for the condition autosomal dominant or recessive? Q11 - Identify the genotype for each individual using the above table. Use A_ if undetermined. Part IV - The Blue People Of Troublesome Creek Six generations after a French orphan named Martin Fugate settled on the banks of eastern Kentucky's Troublesome Creek with his redheaded American bride, his great-great-great-great grandson was born in a modern hospital not far from where the creek still runs. The boy inherited his father's lankiness and his mother's slightly nasal way of speaking. What he got from Martin Fugate was dark blue skin. "It was almost purple," his father recalls. Doctors were so astonished by the colour of Benjy Stacy's skin that they raced him by ambulance from the maternity ward in the hospital near Hazard to a medical clinic in Lexington. Two days of tests produced no explanation for skin the colour of a bruised plum. A transfusion was being prepared when Benjy's grandmother spoke up. "Have you ever heard of the blue Fugates of Troublesome Creek?" she asked the doctors. "My grandmother Luna on my dad's side was a blue Fugate. It was real bad in her," Alva Stacy, the boy's father, explained. The doctors finally came to the conclusion that Benjy's colour was due to blood inherited from generations back. Benjy lost his blue tint within a few weeks, and now he is about as normal looking a seven-year-old boy as you could hope to find. His lips and fingernails still turn a shade of purple-blue when he gets cold or angry, a quirk that so intrigued medical students after Benjy's birth that they would crowd around the baby and try to make him cry. "Benjy was a pretty big item in the hospital," his mother says with a grin. Dark blue lips and fingernails are the only traces of Martin Fugate's legacy left in the boy; that, and the recessive gene that has shaded many of the Fugates and their kin blue for the past 162 years. Given below is a pedigree of some of the blue people of Troublesome Creek
Part III - Trait Analysis
1. The following pedigrees will be used to determine whether the trait is autosomal dominant or
autosomal recessive. In tracing autosomal alleles, if both parents have the disorder and the offspring
do not, the condition is autosomal dominant. If neither parent shows the disorder but some of their
children do, the condition is autosomal recessive. A carrier is an individual who appears to be
normal, but who is capable of passing on a gene for the disorder. If the characteristic is dominant,
there can be no carriers because only a single gene is needed to show the disorder. Table II provides
some keys for your answers.
Table II - Pedigree Keys
Characteristic
Autosomal Dominant
Autosomal Recessive
Figure IV - Pedigree 1
먹어어머머
Key
AA = Affected
Aa Affected
aa = Normal
AA = Normal
Aa = Carrier
aa = Affected
I go
Q8 - Is the gene for the condition autosomal dominant or recessive?
Q9 - Identify the genotype for each individual using the above table. Use A_ if undetermined.
Transcribed Image Text:Part III - Trait Analysis 1. The following pedigrees will be used to determine whether the trait is autosomal dominant or autosomal recessive. In tracing autosomal alleles, if both parents have the disorder and the offspring do not, the condition is autosomal dominant. If neither parent shows the disorder but some of their children do, the condition is autosomal recessive. A carrier is an individual who appears to be normal, but who is capable of passing on a gene for the disorder. If the characteristic is dominant, there can be no carriers because only a single gene is needed to show the disorder. Table II provides some keys for your answers. Table II - Pedigree Keys Characteristic Autosomal Dominant Autosomal Recessive Figure IV - Pedigree 1 먹어어머머 Key AA = Affected Aa Affected aa = Normal AA = Normal Aa = Carrier aa = Affected I go Q8 - Is the gene for the condition autosomal dominant or recessive? Q9 - Identify the genotype for each individual using the above table. Use A_ if undetermined.
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