I understand that Phenylketonuria, or PKU is recessive and that by looking at the pedigree analysis that Ryan and Natalie are mother/son, but I don't understand the genotypes for Max and Kate.   Thanks for any help.

Human Anatomy & Physiology (11th Edition)
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I understand that Phenylketonuria, or PKU is recessive and that by looking at the pedigree analysis that Ryan and Natalie are mother/son, but I don't understand the genotypes for Max and Kate.

 

Thanks for any help.

**11. Analyze a Pedigree of Inheritance of Phenylketonuria**

Phenylketonuria, or PKU, results from an inability to metabolize the amino acid phenylalanine. If untreated, PKU leads to mental retardation.

**a. By observing this pedigree analysis below, is Phenylketonuria, or PKU, inherited as a dominant or recessive trait?**  
___________________________

**Diagram Explanation:**

The pedigree chart displays a family tree with symbols representing individuals and their genotypes related to PKU. Circles denote females, and squares denote males. Shaded symbols represent individuals who express the trait for PKU, while unshaded symbols represent those who do not.

- **First Generation:**  
  - Kate (female, unshaded)  
  - Joe (male, unshaded)

- **Second Generation:**  
  - Curtis (male, shaded)  
  - Anne (female, unshaded)  
  - Max (male, shaded)  
  - Natalie (female, unshaded)

- **Third Generation:**  
  - Devon (male, unshaded)  
  - Ken (male, unshaded)  
  - Kimberly (female, unshaded)  
  - Ryan (male, unshaded)  
  - Donna (female, shaded)

**Questions:**

**b. What is Max’s genotype for PKU?**  
___________________________

**c. What is Kate’s genotype for PKU?**  
___________________________

**d. What is the relationship between Ryan and Natalie?**  
___________________________
Transcribed Image Text:**11. Analyze a Pedigree of Inheritance of Phenylketonuria** Phenylketonuria, or PKU, results from an inability to metabolize the amino acid phenylalanine. If untreated, PKU leads to mental retardation. **a. By observing this pedigree analysis below, is Phenylketonuria, or PKU, inherited as a dominant or recessive trait?** ___________________________ **Diagram Explanation:** The pedigree chart displays a family tree with symbols representing individuals and their genotypes related to PKU. Circles denote females, and squares denote males. Shaded symbols represent individuals who express the trait for PKU, while unshaded symbols represent those who do not. - **First Generation:** - Kate (female, unshaded) - Joe (male, unshaded) - **Second Generation:** - Curtis (male, shaded) - Anne (female, unshaded) - Max (male, shaded) - Natalie (female, unshaded) - **Third Generation:** - Devon (male, unshaded) - Ken (male, unshaded) - Kimberly (female, unshaded) - Ryan (male, unshaded) - Donna (female, shaded) **Questions:** **b. What is Max’s genotype for PKU?** ___________________________ **c. What is Kate’s genotype for PKU?** ___________________________ **d. What is the relationship between Ryan and Natalie?** ___________________________
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