Homework Help is Here – Start Your Trial Now!
Science
Biology
Autosomal Recessive Problem: What is probability of individual 2 III in pedigree 1 and individual 1 III in pedigree 2 to have an affect child?

Autosomal Recessive Problem: What is probability of individual 2 III in pedigree 1 and individual 1 III in pedigree 2 to have an affect child?

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
See similar textbooks
icon
Related questions
Question
Autosomal Recessive Problem: What is probability of individual 2 III in pedigree 1 and individual 1 III in pedigree 2 to have an affect child?
**Phenylketonuria (PKU) - Autosomal Recessive Inheritance** **Pedigree Analysis** *Explanation:* The diagram consists of two pedigrees showing the inheritance pattern of PKU, a genetic disorder inherited in an autosomal recessive manner. Each circle represents a female, and each square represents a male. Shaded symbols indicate individuals affected by PKU. **Pedigree 1:** - **Generation I:** - Individual 1 (square) is shaded, indicating he is affected by PKU. - Individual 2 (circle) is not shaded. - **Generation II:** - Individuals 1 and 2 are connected; neither is shaded. - Individual 3 is married to individual 4; individual 3 is not shaded while individual 4 is not depicted to be shaded. - **Generation III:** - Individual 3 is a female, shaded, indicating she is affected by PKU. - Other individuals (1, 2, 4, 5, 6, and 7) are not shaded. **Pedigree 2:** - **Generation I:** - Individual 2 (circle) is shaded, indicating she is affected by PKU. - Individual 1 (square) is not shaded. - **Generation II:** - Individual 3 is married to individual 4; neither is shaded. - Individual 1 and 2 (circles) are not shaded. - **Generation III:** - Individual 2 is a male, shaded, indicating he is affected by PKU. - Other individuals (1, 3, 4, 5) are not shaded. *Summary:* PKU is inherited in an autosomal recessive pattern, meaning two copies of the mutated gene are required for a person to be affected. Individuals who are shaded in these pedigrees have inherited both recessive alleles.
Transcribed Image Text:**Phenylketonuria (PKU) - Autosomal Recessive Inheritance** **Pedigree Analysis** *Explanation:* The diagram consists of two pedigrees showing the inheritance pattern of PKU, a genetic disorder inherited in an autosomal recessive manner. Each circle represents a female, and each square represents a male. Shaded symbols indicate individuals affected by PKU. **Pedigree 1:** - **Generation I:** - Individual 1 (square) is shaded, indicating he is affected by PKU. - Individual 2 (circle) is not shaded. - **Generation II:** - Individuals 1 and 2 are connected; neither is shaded. - Individual 3 is married to individual 4; individual 3 is not shaded while individual 4 is not depicted to be shaded. - **Generation III:** - Individual 3 is a female, shaded, indicating she is affected by PKU. - Other individuals (1, 2, 4, 5, 6, and 7) are not shaded. **Pedigree 2:** - **Generation I:** - Individual 2 (circle) is shaded, indicating she is affected by PKU. - Individual 1 (square) is not shaded. - **Generation II:** - Individual 3 is married to individual 4; neither is shaded. - Individual 1 and 2 (circles) are not shaded. - **Generation III:** - Individual 2 is a male, shaded, indicating he is affected by PKU. - Other individuals (1, 3, 4, 5) are not shaded. *Summary:* PKU is inherited in an autosomal recessive pattern, meaning two copies of the mutated gene are required for a person to be affected. Individuals who are shaded in these pedigrees have inherited both recessive alleles.
Expert Solution
Step 1

Autosomal recessive disease occurs when both the alleles are mutated.  2 heterozygous parents will produce and affected child and is probability is always 1/4.

steps

Step by step

Solved in 2 steps

SEE SOLUTIONCheck out a sample Q&A here
Blurred answer
Similar questions
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:
9780134580999
Author:
Elaine N. Marieb, Katja N. Hoehn
Publisher:
PEARSON
Biology 2e
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
Anatomy & Physiology
Anatomy & Physiology
Biology
ISBN:
9781259398629
Author:
McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:
Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:
9780815344322
Author:
Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:
W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:
9781260159363
Author:
Martin, Terry R., Prentice-craver, Cynthia
Publisher:
McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Inquiry Into Life (16th Edition)
Biology
ISBN:
9781260231700
Author:
Sylvia S. Mader, Michael Windelspecht
Publisher:
McGraw Hill Education
SEE MORE TEXTBOOKS