Part 1. Define heritability and the impact of the environment on the heritability of a trait. Give an example of an environmental factor that can impact risk for cancer. Part 2. Estimates of heritability have been generally low across cancers (<15%), yet there has been a great interest in sequencing tumors using exome-sequencing or whole genome sequencing to identify genetic causes of each cancer. Given the low heritability of nearly all cancers, should we expect to find a genetic cause for most cancer cases? Why or why not? Hint: Think about common genetic causes of cancer and ask yourself whether they are captured by heritability.
Part 1. Define heritability and the impact of the environment on the heritability of a trait. Give an example of an environmental factor that can impact risk for cancer. Part 2. Estimates of heritability have been generally low across cancers (<15%), yet there has been a great interest in sequencing tumors using exome-sequencing or whole genome sequencing to identify genetic causes of each cancer. Given the low heritability of nearly all cancers, should we expect to find a genetic cause for most cancer cases? Why or why not? Hint: Think about common genetic causes of cancer and ask yourself whether they are captured by heritability.
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Part 1. Define heritability and the impact of the environment on the heritability of a trait. Give an example of an environmental factor that can impact risk for cancer. Part 2. Estimates of heritability have been generally low across cancers (<15%), yet there has been a great interest in sequencing tumors using exome-sequencing or whole genome sequencing to identify genetic causes of each cancer. Given the low heritability of nearly all cancers, should we expect to find a genetic cause for most cancer cases? Why or why not? Hint: Think about common genetic causes of cancer and ask yourself whether they are captured by heritability.
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