Which of the following best describes the effects of inheriting one copy of a loss-of-function mutation in a gene coding for a protein involved in DNA repair? Selected answer will be automatically saved. For keyboard navigation, press up/down arrow keys to select an answer. a b It would increase cancer susceptibility because it would be a dominant mutation at the molecular level. C It would have little effect on cancer susceptibility because most cancer results from somatic mutations. d It would increase cancer susceptibility because a somatic mutation in the other copy would result in defective DNA repair in some cell lineages. It would have little effect on cancer susceptibility because the other functional copy of the gene would result in effective DNA repair.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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1.

Which of the following best describes the effects of inheriting one
copy of a loss-of-function mutation in a gene coding for a protein
involved in DNA repair?
Selected answer will be automatically saved. For keyboard navigation, press
up/down arrow keys to select an answer.
a
It would have little effect on cancer susceptibility because
most cancer results from somatic mutations.
b
It would increase cancer susceptibility because it would be
a dominant mutation at the molecular level.
с
It would increase cancer susceptibility because a somatic
mutation in the other copy would result in defective DNA
repair in some cell lineages.
It would have little effect on cancer susceptibility because
the other functional copy of the gene would result in
effective DNA repair.
Transcribed Image Text:Which of the following best describes the effects of inheriting one copy of a loss-of-function mutation in a gene coding for a protein involved in DNA repair? Selected answer will be automatically saved. For keyboard navigation, press up/down arrow keys to select an answer. a It would have little effect on cancer susceptibility because most cancer results from somatic mutations. b It would increase cancer susceptibility because it would be a dominant mutation at the molecular level. с It would increase cancer susceptibility because a somatic mutation in the other copy would result in defective DNA repair in some cell lineages. It would have little effect on cancer susceptibility because the other functional copy of the gene would result in effective DNA repair.
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