Answered: On block 1 (Glycogen Metabolism) fill…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Related questions

Question

On block 1 (Glycogen Metabolism) fill in the missing pathway (beginning at G6P and ending
at Glycogen (n+1)). Names of enzymes and chemical structures of intermediates are NOT
needed, rather only names of each intermediate. Also, you can assume that a
glycogenin core has already been built. On this same block the student needs to show the
opposing pathway starting at glycogen n+1 and proceeding to G6P.

On block 2 (Glycolysis) fill in the missing pathway (beginning at glucose and
ending at 2 pyruvate). Names of enzymes and chemical structures of intermediates are NOT

needed, rather only names of each intermediate. From pyruvate illustrate the fate of pyruvate
in anaerobic conditions and the two products produced by this fate.

### Diagram Explanation

This image illustrates the conversion of glucose to glucose-6-phosphate (G6P) and the involvement of ATP in this process.

#### Section 1:
- **G6P**: This is glucose-6-phosphate, which acts as both a substrate and product in metabolic processes.

#### Section 2:
- **Glucose Conversion**: Glucose is phosphorylated to form glucose-6-phosphate (G6P).
- **ATP to ADP**: This conversion involves the use of ATP (adenosine triphosphate), which is converted to ADP (adenosine diphosphate) during the process.

The diagram visually represents the direction of the conversion, flowing from glucose to G6P, highlighting the essential roles of ATP and ADP.

Expert Solution

Step 1: Understanding what is Glycogen metabolism

Glycogen metabolism is the process by which glucose-6-phosphate is changed into the branched glucose polymer known as glycogen. Enzymes such as UDP-glucose pyrophosphorylase are involved in the process. When energy is required, glycogen may be broken down to release glucose. Through an opposite mechanism, enzymes like glucose-6-phosphatase and glycogen phosphorylase change glycogen back into glucose-6-phosphate.