A biosynthetic pathway for the synthesis of two molecules, E or H, from molecule A is shown below. Letters A through H represent molecules, and numbers 1 through 7 represent enzymes. Observe that after the formation of molecule C, either molecule E or H can be formed depending on which pathway is followed. Note that if a build up of molecule H occurs at a high enough concentration, it impedes the action of enzyme 5 (that is what the curve to flat lines indicate). D4E 2 3 5 1 A B B- F 6 G7 H

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
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Chapter1: Biochemistry: An Evolving Science
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**Biosynthetic Pathway for Molecule Synthesis**

In this diagram, we present a biosynthetic pathway for synthesizing two molecules, E or H, from molecule A. Here's the breakdown:

- **Molecules**: Denoted by letters A through H.
- **Enzymes**: Represented by numbers 1 through 7.

### Pathway Overview:

1. **A to B** via Enzyme 1
2. **B to C** via Enzyme 2
3. **C to D** via Enzyme 3
4. **D to E** via Enzyme 4
5. **C to F** via Enzyme 5
6. **F to G** via Enzyme 6
7. **G to H** via Enzyme 7

### Pathway Details:

- After forming molecule C, the pathway can diverge to form either molecule E or H.
- High concentrations of molecule H can impede the action of enzyme 5, as indicated by the curve leading to flat lines.

### Questions:

**A. What is the original reactant in the above pathways?**  
- [Select]

**B. Name an intermediate product in the pathway from molecule A to molecule E.**  
- [Select]

**C. Name an intermediate product in the pathway from molecule C to molecule H.**  
- [Select]

**D. Name a final product of this pathway.**  
- [Select]

**E. If there is a high concentration of molecule E, which enzyme will be inhibited?**  
- [Select]

**F. Will the synthesis of molecule H then increase (I) or decrease (D)?**  
- [Select]

**G. What type of enzyme regulation is this an example of?**  
- [Select]
Transcribed Image Text:**Biosynthetic Pathway for Molecule Synthesis** In this diagram, we present a biosynthetic pathway for synthesizing two molecules, E or H, from molecule A. Here's the breakdown: - **Molecules**: Denoted by letters A through H. - **Enzymes**: Represented by numbers 1 through 7. ### Pathway Overview: 1. **A to B** via Enzyme 1 2. **B to C** via Enzyme 2 3. **C to D** via Enzyme 3 4. **D to E** via Enzyme 4 5. **C to F** via Enzyme 5 6. **F to G** via Enzyme 6 7. **G to H** via Enzyme 7 ### Pathway Details: - After forming molecule C, the pathway can diverge to form either molecule E or H. - High concentrations of molecule H can impede the action of enzyme 5, as indicated by the curve leading to flat lines. ### Questions: **A. What is the original reactant in the above pathways?** - [Select] **B. Name an intermediate product in the pathway from molecule A to molecule E.** - [Select] **C. Name an intermediate product in the pathway from molecule C to molecule H.** - [Select] **D. Name a final product of this pathway.** - [Select] **E. If there is a high concentration of molecule E, which enzyme will be inhibited?** - [Select] **F. Will the synthesis of molecule H then increase (I) or decrease (D)?** - [Select] **G. What type of enzyme regulation is this an example of?** - [Select]
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