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Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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### Explanation of Immune Cell Interaction

#### Description

This diagram depicts the interaction between immune cells, specifically focusing on antigen presentation and recognition processes.

1. **Diagram A - T Lymphocyte (T Cell)**
   - This is a red-colored round cell labeled "A".
   - T lymphocytes are a type of white blood cell crucial for immune responses.

2. **Diagram B - Dendritic Cell (Antigen Presenting Cell)**
   - This is an orange-colored cell with protruding extensions, labeled "B".
   - Dendritic cells capture and process microbial, tumor, or normal self-proteins and present them to T cells.

3. **Class II MHC (Major Histocompatibility Complex)**
   - A green structure interacting with both the TCR on the T cell and the antigen on the dendritic cell.
   - Class II MHC molecules present processed peptide fragments to T cells.

4. **TCR (T Cell Receptor)**
   - A red structure on the T cell that binds to the MHC-antigen complex.

5. **C - CD4 Molecules**
   - Labeled "C", indicating their involvement in the interaction between Class II MHC and TCR.
   - CD4 molecules are typically associated with helper T cells.

#### Detailed Description of Processes

**Peptide Presentation:**
- **Peptides** derived from phagocytosed and lysosome-processed proteins (microbial, tumor, or self-antigens) are displayed on the surface of dendritic cells using Class II MHC molecules.
- The dendritic cell presents these antigens to T cells via the interaction between MHC molecules and TCR, aided by CD4 molecules.

**Quiz Question:**
Identify the incorrect statement from the following options:
1. A is a B lymphocyte 
2. A is a T lymphocyte 
3. C is CD4 molecules 
4. B is a dendritic cell 
5. B is an antigen presenting cell

#### Answer
The incorrect statement is:
- **A is a B lymphocyte**

This question tests understanding of immune cell types and their functions.

### Additional Reading:
- To learn more about immune responses, explore resources on cellular immunity, antigen presentation, and the roles of different immune cells.
Transcribed Image Text:### Explanation of Immune Cell Interaction #### Description This diagram depicts the interaction between immune cells, specifically focusing on antigen presentation and recognition processes. 1. **Diagram A - T Lymphocyte (T Cell)** - This is a red-colored round cell labeled "A". - T lymphocytes are a type of white blood cell crucial for immune responses. 2. **Diagram B - Dendritic Cell (Antigen Presenting Cell)** - This is an orange-colored cell with protruding extensions, labeled "B". - Dendritic cells capture and process microbial, tumor, or normal self-proteins and present them to T cells. 3. **Class II MHC (Major Histocompatibility Complex)** - A green structure interacting with both the TCR on the T cell and the antigen on the dendritic cell. - Class II MHC molecules present processed peptide fragments to T cells. 4. **TCR (T Cell Receptor)** - A red structure on the T cell that binds to the MHC-antigen complex. 5. **C - CD4 Molecules** - Labeled "C", indicating their involvement in the interaction between Class II MHC and TCR. - CD4 molecules are typically associated with helper T cells. #### Detailed Description of Processes **Peptide Presentation:** - **Peptides** derived from phagocytosed and lysosome-processed proteins (microbial, tumor, or self-antigens) are displayed on the surface of dendritic cells using Class II MHC molecules. - The dendritic cell presents these antigens to T cells via the interaction between MHC molecules and TCR, aided by CD4 molecules. **Quiz Question:** Identify the incorrect statement from the following options: 1. A is a B lymphocyte 2. A is a T lymphocyte 3. C is CD4 molecules 4. B is a dendritic cell 5. B is an antigen presenting cell #### Answer The incorrect statement is: - **A is a B lymphocyte** This question tests understanding of immune cell types and their functions. ### Additional Reading: - To learn more about immune responses, explore resources on cellular immunity, antigen presentation, and the roles of different immune cells.
Expert Solution
Step 1

The given diagram is of ANTIGEN PRESENTATION to a defence cell of the body so that it recognises the antigen & acts accordingly.

ANTIGEN PRESENTATION is the foremost step towards defending the body from antigens. It is carried out by ANTIGEN PRESENTING CELLS, mostly Dendritic cells.

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