Please help fill out the metabolic Pathway table of Glycolysis and Pentose-Phosphate Pathway Pentose-Phosphate PathwayECReactionGlucose-6-phosphate dehydrogenase 1.1.1.49 Glucose-6-phosphate →6-PhosphogluconolactoneEnzymegluconoactonaseribulose-5-phosphate isomeraseribulose-5-phosphate 3-epimeraseTransketolaseTransaldolase3.1.1.175.3.1.65.1.3.12.2.1.12.2.1.2AG(kJ/mol)-24.77NADPCofactorsRegulationG6PD is affected by the ratioNADPH + HNotesG6PD is the only source of NADPHin erythrocytes/G6PD deficiency leads to hemolysis/NADP*. With low [NADPH + H]the enzyme activity increases.Positive regulators: Insulin, Vit D,PI3-kinase, etc.Negative regulators: Aldosterone,arachidonic acid, CAMP, p53, etc.when the body is exposed to certainfoods, drugs, infections, or stress.Symptoms may include dark urine,fatigue, paleness, rapid heart rate,and jaundice.G6PD deficiency is inherited in anX-linked recessive (Stanton, 2012) isent rows il necessaryGlycolysisHexokinasePhosphoglucose IsomerasePhosphofructokinase-1AldlaseEnzymeTriosephosphate kinaseGlyceraldehyde 3- phosphatedehydrogenasePhosphoglyceromutaseEnolasePhosphoglyceromutasePyruvaate kinaseEC2.7.1.15.3.1.91.112.135.3.1.11.2.1.125.4.2.114.2.1.115.4.2.122.7.1.40ReactionGlucose + ATP- G6P + ADP 16.6D-Glucose+ 6 phosphate - D 1.7fructose 6 phosphateΔG"(kJ/mol)fructose-6-phosphate -ADP + fructosedihydroxyacetonfructose 1,6 -biphosphate - 22.8phosphate andglyceraldehyde 3-phosphateDihydroxyaceton phosphate 7.9-glyceraldehyde 3-phosphate.3-phosphoglycerate-2-phosphoglycerate-13.7glyceraldehyde-1,3 bis 6.3phosphoglycerate 3phosphateglucose two 3-carbonmolecules-18.8+/- 103-phosphoglycerate-2-phosphoglyceratePhosphoenolpyruvate + ADP-31.7→ Pyruvate + ATP4.8CofactorsMagnesiumMn2+Callcium, MagnesiumMagnesiumdon't require cofactorsNAD+, NADP+MagnesiumMagnesiumMagnesiumK, MgRegulationAllosteric effects (e.g. fructose-1,6-bisphosphate), phosphorylation onSer12.NotesPyruvate kinase deficiency (PKD) ia rare genetic disordercharacterized by the prematuredestruction of red bloods, which iscalled hemolytic anemia.

Metabolic pathways are series of chemical reactions that occur within a living organism in order to…

Answered: Please help fill out the metabolic…

Science

Biochemistry

Please help fill out the metabolic Pathway table of Glycolysis and Pentose-Phosphate Pathway

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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