Please help fill out the metabolic Pathway table of Glycolysis and Pentose-Phosphate Pathway Pentose-Phosphate PathwayECReactionGlucose-6-phosphate dehydrogenase 1.1.1.49 Glucose-6-phosphate →6-PhosphogluconolactoneEnzymegluconoactonaseribulose-5-phosphate isomeraseribulose-5-phosphate 3-epimeraseTransketolaseTransaldolase3.1.1.175.3.1.65.1.3.12.2.1.12.2.1.2AG(kJ/mol)-24.77NADPCofactorsRegulationG6PD is affected by the ratioNADPH + HNotesG6PD is the only source of NADPHin erythrocytes/G6PD deficiency leads to hemolysis/NADP*. With low [NADPH + H]the enzyme activity increases.Positive regulators: Insulin, Vit D,PI3-kinase, etc.Negative regulators: Aldosterone,arachidonic acid, CAMP, p53, etc.when the body is exposed to certainfoods, drugs, infections, or stress.Symptoms may include dark urine,fatigue, paleness, rapid heart rate,and jaundice.G6PD deficiency is inherited in anX-linked recessive (Stanton, 2012) isent rows il necessaryGlycolysisHexokinasePhosphoglucose IsomerasePhosphofructokinase-1AldlaseEnzymeTriosephosphate kinaseGlyceraldehyde 3- phosphatedehydrogenasePhosphoglyceromutaseEnolasePhosphoglyceromutasePyruvaate kinaseEC2.7.1.15.3.1.91.112.135.3.1.11.2.1.125.4.2.114.2.1.115.4.2.122.7.1.40ReactionGlucose + ATP- G6P + ADP 16.6D-Glucose+ 6 phosphate - D 1.7fructose 6 phosphateΔG"(kJ/mol)fructose-6-phosphate -ADP + fructosedihydroxyacetonfructose 1,6 -biphosphate - 22.8phosphate andglyceraldehyde 3-phosphateDihydroxyaceton phosphate 7.9-glyceraldehyde 3-phosphate.3-phosphoglycerate-2-phosphoglycerate-13.7glyceraldehyde-1,3 bis 6.3phosphoglycerate 3phosphateglucose two 3-carbonmolecules-18.8+/- 103-phosphoglycerate-2-phosphoglyceratePhosphoenolpyruvate + ADP-31.7→ Pyruvate + ATP4.8CofactorsMagnesiumMn2+Callcium, MagnesiumMagnesiumdon't require cofactorsNAD+, NADP+MagnesiumMagnesiumMagnesiumK, MgRegulationAllosteric effects (e.g. fructose-1,6-bisphosphate), phosphorylation onSer12.NotesPyruvate kinase deficiency (PKD) ia rare genetic disordercharacterized by the prematuredestruction of red bloods, which iscalled hemolytic anemia.

Metabolic pathways are series of chemical reactions that occur within a living organism in order to…

Answered: Please help fill out the metabolic…

Science

Biochemistry

Please help fill out the metabolic Pathway table of Glycolysis and Pentose-Phosphate Pathway

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

See similar textbooks

Related questions

Q: D Question 19 What is the name of the enzyme responsible for removal of one glucosyl unit from the…

A: The enzyme which removes one glucosyl unit from non reducing end if glycogen is glycogen…

Q: In the space below, list ALL redox reactions that occur during cellular respiration. At the end of…

A: Introduction Redox is a chemical reaction that involves changing the oxidation states of atoms.…

Q: choose the metabolic pathway being described in the statement choices: Digestion Glycolysis…

A: Primary essential metabolites are compounds like proteins and carbohydrates which make up the…

Q: Please describe the steps by which the carbons in ketogenic amino acids could be incorporated into…

A: Ketogenic amino acids: The carbon skeletons are catabolized to acetyl-CoA or acetoacetate and can…

Q: what is the Hereditary enzymopathies of pentose phosphate pathway, fructose and galactose metabolism

A: Enzymopathy can be defined as a disorder that results in defective enzymes. It is mainly considered…

Q: Please describe the steps by which insulin would stimulate fatty acid biosynthesis while inhibiting…

A: Hormones are chemical messengers that are involved in signaling pathways. They regulate many…

Q: Which metabolic pathway do you conclude the supplement selenium to most directly affect or interact…

A: Selenium is the element that serves as structural part of two amino acids viz., Selenicysteine and…

Q: Please explain the role of pantothenic acid-derived CoA as a carrier of acetyl group in carbohydrate…

A: Coenzyme A is required for the metabolism of carbohydrates. Pantothenic acid is the prescursor of…

Q: Glutamate dehydrogenase functions to produce ammonia for the urea cycle. Use the standard reduction…

A: Glutamate dehydrogenase is the enzyme that is responsible for the production of ammonia. Ammonia…

Q: xamine the following reaction and answer the questions below ased on your understanding of enzymes…

A: Biosynthesis is defined as the biochemical reactions that result in the formation of a biomolecule.…

Q: Describe how a product generated from glycolysis can be used for ATP production by the electron…

A: * Glycolysis is a metabolic pathway it converts glucose into pyruvic acid and in this process free…

Q: ___________ is considered an important amphibolic pathway which plays a major role in oxidative…

A: Amphibolic pathway meaning that they can perform both catabolic(breakdown) and anabolic(synthesis)…

Q: /on Gierke's disease is a glycogen storage disease that results from the absence of…

A: Glucose-6-phosphatase converts glucose-6-phosphate to glucose. Absence of glucose-6-phosphatase…

Q: Please explain the concept of a "feed-forward" mechanism and provide an example of this in the…

A: In a feed-forward activation, a metabolite produced early in the pathway activates the enzyme that…

Q: I need a simple explanation of what PFK1 and PFK2 do in glycolysis? And what FBPase1 and FBPase2 do…

A: Glycolysis is the breakdown of glucose into pyruvate or lactate. Phosphofructokinase (PFK-1) is a…

Q: This first question asks you to group the different answers into the correct category. Our two…

A: Anabolism uses energy to generate chemicals that the body need for proper operation. Catabolism, on…

Q: Discuss the importance of redox reactions in the metabolism of glucose. Be sure to address…

A: Cellular respiration involves many reactions where electrons are passed from one molecule to…

Q: Answer the following about fatty acid elongation and desaturation: a) Give the specifics of its…

A: Hi! Thank you for posting the question on Bartleby. As per the guidelines we can answer only three…

Q: The metabolic process in all living organisms are relative function of the molecular basic of the…

A: Metabolism is the sum total of all the chemical reactions which take place to sustain life.…

Q: Describe what happens to ALL the end-products of glycolysis in a short paragraph (5-7 sentences). Be…

A: Glycolysis is a metabolic pathway that occurs in the cytoplasm of cells and is the first step in the…

Q: Provide what is being asked for. Show all relevant calculations and summarize your answers in the…

A: Fatty acid oxidation is the aerobic breakdown of a fatty acid into acetyl-CoA units in the…

Q: What are two important compounds that lie at crossroads of major metabolic pathways? Select both…

A: Metabolic pathway engineering in microbial hosts for heterologous biosynthesis of commodity…

Q: list ALL redox reactions that occur during cellular respiration. At the end of your list, how many…

A: Redox reactions involve many reactions from cellular respiration, in which electrons are passed from…

Q: Give a detailed account of the tricarboxylic acid pathway and how it is regulated in eukaryotic…

A: The citric acid cycle (CAC), sometimes referred to as the Krebs cycle and the tricarboxylic acid…

Q: Although both acetyl-CoA and succinyl-CoA are high-energy thioesters, their chemical energy is used…

A: A tricarboxylic acid (TCA) cycle, commonly known as the Krebs or citric acid cycle, is the primary…

Q: DEFINE THE FOLLOWING TERMS A. GLUCONEOGENESIS B. GLYCOLYSIS C. CITRIC ACID CYCLE

A: Since your question has multiple sub-parts, we will solve the first three sub-parts for you. If you…

Q: Describe the defect, identifying the enzyme(s) and discuss the therapy available treatmen

A: Metabolic disorder is a condition affect any aspect of metabolism. metabolism is a biochemical…

Q: You are working in a lab that discovers a small molecule inhibitor that prevents biotin from being…

A: In human, there are many enzymes involved in different pathways. Some of the enzymes requires ions,…

Q: Given: One way to think about the hexokinase is that it couples the hydrolysis of ATP (AG° - -30.5…

A: Hexokinase: Hexokinase phosphorylate Glucose to Glucose-6-PO4 by utilizing one molecule of ATP. Here…

Q: Identify a pathway for utilization of the four carbons of acetoacetate in cholesterol biosynthesis.…

A: Cholesterol is an extremely significant biological molecule that plays a role in the structure of…

Q: Which of the following are correct statements pertaining to the glycolytic pathway? Choose all…

A: Since you have asked multiple question, we will solve the first question for you. If you want any…

Q: Please explain the requirement for ATP in the overall process of fatty acid biosynthesis. Enter your…

A: ATP is the primary energy storage molecule found in the cell due to the presence of high-energy…

Q: Structural Formula of the Enzyme, activator and Structural formula of the product reversible or…

A: By gluconeogenesis, organisms produce sugars (particularly glucose) from non-carbohydrate sources…

Q: Cellular respiration is an example of an anabolic and endergonic reaction a catabolic and exergonic…

A: Respiration is a catabolic, biochemical process, that involves the stepwise, complete or incomplete…

Q: Explain how G protein enzymatic activity and signaling activity relates to guanine nucleotides.

A: G proteins, otherwise called guanine nucleotide-restricting proteins, are a group of proteins that…

Q: AMP is an activator of fructose 1,6-bisphosphatase (FBPase-1) True False

A: Glycolysis is the process by which one molecule of 6 carbon glucose is broken down into 2 molecules…

Q: CHOOSE THE CORRECT LETTER There are four enzymes of gluconeogenesis that circumvent the…

A: Gluconeogenesis is synthesis of glucose from pyruvate.

Q: Please answer yes or no with a short explanation. Thank you By chemical nature, cytochromes are…

A: Electron transport chain or ETC is a pathway in which NADH and FADH2 molecules get oxidized. There…

Q: Describe how the cholesterol from the burger ultimately gets to your liver. In Your answer mention…

A: A metabolic pathway is a series of interconnected chemical reactions that occur within a cell or…

Q: If you perform fatty acid biosynthesis where ALL the malonyl-CoA is labeled at EVERY carbon with…

A: The fatty acid is a long chain of hydrocarbon that contains the carboxyl group as its functional…

Q: 2. Using your notes on the citric acid cycle, What is the name of the enzyme that does the…

A: Cellular respiration is a collection of three metabolic pathways that generate ATP by the oxidation…

Question

Please help fill out the metabolic Pathway table of Glycolysis and Pentose-Phosphate Pathway

Pentose-Phosphate Pathway
EC
Reaction
Glucose-6-phosphate dehydrogenase 1.1.1.49 Glucose-6-phosphate →
6-Phosphogluconolactone
Enzyme
gluconoactonase
ribulose-5-phosphate isomerase
ribulose-5-phosphate 3-epimerase
Transketolase
Transaldolase
3.1.1.17
5.3.1.6
5.1.3.1
2.2.1.1
2.2.1.2
AG
(kJ/mol)
-24.77
NADP
Cofactors
Regulation
G6PD is affected by the ratio
NADPH + H
Notes
G6PD is the only source of NADPH
in erythrocytes/
G6PD deficiency leads to hemolysis
/NADP*. With low [NADPH + H]
the enzyme activity increases.
Positive regulators: Insulin, Vit D,
PI3-kinase, etc.
Negative regulators: Aldosterone,
arachidonic acid, CAMP, p53, etc.
when the body is exposed to certain
foods, drugs, infections, or stress.
Symptoms may include dark urine,
fatigue, paleness, rapid heart rate,
and jaundice.
G6PD deficiency is inherited in an
X-linked recessive (Stanton, 2012)

isent rows il necessary
Glycolysis
Hexokinase
Phosphoglucose Isomerase
Phosphofructokinase-1
Aldlase
Enzyme
Triosephosphate kinase
Glyceraldehyde 3- phosphate
dehydrogenase
Phosphoglyceromutase
Enolase
Phosphoglyceromutase
Pyruvaate kinase
EC
2.7.1.1
5.3.1.9
1.11
2.13
5.3.1.1
1.2.1.12
5.4.2.11
4.2.1.11
5.4.2.12
2.7.1.40
Reaction
Glucose + ATP- G6P + ADP 16.6
D-Glucose+ 6 phosphate - D 1.7
fructose 6 phosphate
ΔG"
(kJ/mol)
fructose-6-phosphate -
ADP + fructose
dihydroxyaceton
fructose 1,6 -biphosphate - 22.8
phosphate and
glyceraldehyde 3-phosphate
Dihydroxyaceton phosphate 7.9
-glyceraldehyde 3-
phosphate.
3-phosphoglycerate-2-
phosphoglycerate
-13.7
glyceraldehyde-1,3 bis 6.3
phosphoglycerate 3
phosphate
glucose two 3-carbon
molecules
-18.8
+/- 10
3-phosphoglycerate-2-
phosphoglycerate
Phosphoenolpyruvate + ADP-31.7
→ Pyruvate + ATP
4.8
Cofactors
Magnesium
Mn2+
Callcium, Magnesium
Magnesium
don't require cofactors
NAD+, NADP+
Magnesium
Magnesium
Magnesium
K, Mg
Regulation
Allosteric effects (e.g. fructose-1,6-
bisphosphate), phosphorylation on
Ser12.
Notes
Pyruvate kinase deficiency (PKD) i
a rare genetic disorder
characterized by the premature
destruction of red bloods, which is
called hemolytic anemia.

Chemical pathways by which living things function, especially those that provide cellular energy, such as the transformation of energy from food into the energy of ATP. Metabolism also focuses on chemical pathways involving the synthesis of new biomolecules and the elimination of waste.

Expert Solution

This question has been solved!

Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.

SEE SOLUTION Check out a sample Q&A here

Step 1: Introduction

VIEW

Step 2: Pentose phosphate pathway

VIEW

Solution

VIEW

Step by step

Solved in 3 steps with 1 images

SEE SOLUTION Check out a sample Q&A here

Similar questions

State the steps of the beta-oxidation pathway. Please make sure to state all the enzymes and co-factors for each reaction. please write it short and clear steps.
Please draw all of the structures of the intermediates and names of all reactants, intermediates and products, as well as the names of the enzymes. Draw the whole pathway for the catabolism of fructose into 2 lactates as it occurs in muscle tissue.
Write down the chemical reactions with intermediates, enzymes, and coenzymes that are involved in the conversion of glucose to glycogen (no need to list the substances, suffice it to name them).
How many molecules of ATP energy can a molecule of Asp be generated in the human body by thorough oxidation and decomposition (including ammonia metabolism)? Please write down the metabolic process in detail, including the names of substrates, products and enzymes at each step (metabolic processes involved in the urea cycle can be written directly into the urea cycle without details).
Please answer this with the simplest answer , Please bolt the important answer
Name and explain in detail one pathological condition/state in which the activity of succinate dehydrogenase would decrease in human cells. You should describe the mechanism by which the condition/state affects the activity of enzyme.
Which of the following are correct statements pertaining to the glycolytic pathway? Choose all correct statements. Glucose is a substrate for the first reaction of glycolysis, Glycolysis is an aerobic process Glycolysis takes place in the cytoplasm of the cell. Glycolysis is the process by which glucose is converted to acetyl CoA Major products of glycolysis include pyruvate, ATP and NADH Dago Next Page Page 31 of 36
please explain the catalytic mechanism of phenylalanine hydroxylase in detail. thank you! (biochemistry, chemistry based)
Please describe the functions of the pentose phosphate pathway. Explain how NADPH functions in biosynthesis of fatty acid and deoxyribonucleotide.
Please answer fast
Degradation of normal glycogen results to 97.2% glucose 1-phosphate and 7.2% glucose. Assuming a ratio of glucose 1-phosphate to glucose recorded in a glycogen sample from a patient with a liver disease was 100, The patient’s most likely enzymatic deficiency is _________
Please answer yes or no and give a explanation please, thank you :) -Can acetone be formed from acetoacetic acid? -Acetyl-CoA - is the only source of formation of acetone bodies in the body, isn’t it?