OH HNL CN R' + HCN One of the proposed mechanisms for this enzyme is shown in the scheme below. His235 Ser80 His235 Asp207 Sor0 O--H-N N -Thr" Asp207. O-H-N Thr" H. (a) Lys?3O NH3 Lys236 NH3 (d) NEC- OH HCN H20 H20

Q: Draw a mechanism for the below, which involves two steps and the star point of the enzyme (on the…

A: To draw a mechanism for the below, which involves two steps, and the starting point of the enzyme…

Q: multiple choice, choose the correct answer When substrate concentration is increased for a simple…

A: In Enzyme substrate reaction , substrate bind the active site .

Q: Draw the mechanism of the following hydrolysis Hi excess H₂O CH3NH₂

A: Given,The reaction:

Q: What is the major product from this reaction? HBr (2 equiv) Br Br Br Compound A ● Compound B…

A: Since you have asked multiple questions, we will answer the first question for you as per our…

Q: Ph3P. Pd" Ph3P" transmetalation

A:

Q: Me O Me -Me OTIPS Mo Mo OH ***/22 32 and 32: Me n-BuдNF, ACOH THF, 0 °C Me 0. Mo -Me OU Me Me O.H HO

A:

Q: 12. What is the significance of the following stereochemical result: Co0 COo- mutase H- OH CH OP…

A: Isotopic labelling is one of the ways to track the movement of atoms in any mechanism. Mutase enzyme…

Q: Suppose that, in the absence of enzyme, the forward rate constant, kf, for the conversion of S to P…

A: Keq = KF/KR  Keq = Equilibrium rate constant KR = Rate constant for reverse reaction  KF = Rate…

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A: The major product for the given reaction sequence can be predicted as :   Step 1 : The given alkene…

Q: which enzyme mostly carried the following reaction NH2 indomethacin desisopropyl indomethacin

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A:

Q: Identify the reaction products the corresponding reaction mechanisms för the following chemical…

A:

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A: Structure of PLP is as follows: In the first step aldehyde group of the coenzyme forms the imine…

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A: The racemization of proline is facilitated by the enzyme, proline racemase and the racemization of…

Q: 26. Which of the following is an important intermediate of the reaction sequence shown in the box?…

A: ->gilmann reagent ((CH3)2CuLi) give Michael addition reaction when reacts with alpha-beta…

Q: Which of the following compounds contains one or more protons that could be exchanged with D20? to.…

A:

Q: mutistriatin Hg C -CH3 3C H+ H2 O

A:

Q: None

A: The question is confusing as the proper reaction is not stated. If the reaction involves addition of…

Q: Identify the electrophilic centre that is attacked on the structure of parecoxib. For this question…

A:

Q: 8. (a) Draw a mechanism for the following enzymatic reaction. .coo HS NH, "OOC. `NH3* `NH,* coo NH3*…

A: Cysteine is an amino acid having formula HOCCH2(NH)CH2SH. It undergoes enzymatic reaction to form…

Q: b) c) SO₂Ph TMS Pd(OAc)2 Et3N, 100 °C Pd(OAc)2 PPh3, r.t. TMS a + SO₂Ph + SO₂Ph

A:

Q: Metalloproteases can contain a catalytic triad made up o O D(H₂O)D E(Ln*)S None of the choices are…

A:

Q: Does some one know how to draw the mechanism? он R2 lipase R? pH 7.0 buffer R? R' R' R1 R' = H, R? =…

A: 4) Given,

Q: 24-33 Predict the product(s) and provide the mechanism for each reaction below. (a) 1. NaN3 2. H20,…

A: Curtius rearrangement : Acyl chloride reaction with NaN3, H2O, heat produces primary amines ( see…

Q: Isotopic labeling is very important in tracking compounds biologically and chemically in helping to…

A:

Q: 1) NaOEt Me OEt 2) H30* Could you show the mechanism please, also how do you know which alpha…

A: Given : We have to write the product for the given reaction.

Q: Assume you are studying a hydrolase that catalyzes the following reaction which has a ΔGO of + 27…

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Q: 4. Provide the mechanism for the conversion of heroin to morphine below using only the esterase…

A: Solution: Mechanism for the ester is described below

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A:

Q: 2.2 Suppose that the following sequence describes the reactions of two different substrates…

A: solution               Find the rate of equation by making the Michaelis - Menten assumption = ?

Q: H Soy マ20 H. +H20 OH + Hz0

A:

Q: Draw curved arrows to show the mechanism for the step of the B-ketoacyl-ACP synthase reaction shown…

A: In given reaction release of CO2 takes place.

Q: NH₂ CN MgBr NH₂ C=NH COOC₂Hs COOCs H₂N-CH H OH NOH >C00C,H, KOH -COOK

A: A series of reactions are given in above question, we have to draw the mechanism for the reaction.

Q: 7- Uricase acts on uric acid to produce allantoin, carbon dioxide andhydrogen peroxide. Hydrogen…

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Q: Draw a reaction mechanism to account for the formation of the dipeptide (cy = cyclohexyl)

A:

Q: [deprotonation of triple bond] [rka 25] 0 & 0 t NHs [vka 38] CHs by &

A:

Q: Oxaloacetic acid (or 2-ketosuccinic acid) is a very important intermediate in metabolism. The…

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Q: The following reaction is catalyzed by a PLP-dependent enzyme. Propose a mechanism for this…

A: Enzyme extract the proton adjacent to carboxyl group. One carboanion is formed after that carboanion…

Q: Phosphoglycerate mutase mechanism is shown below: Phosphoglycerate mutase His His 2-0,pN+ "ooc…

A: We have to explain the following given mechanism for the four questions:

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A: The impure substances have lower melting point.

Q: Why would adding Na I catalyze this rxn? CI + NaOH OH + NaCl

A:

Q: Find the product of this enzyme catalyzed reaction.

A: In this question, we will find out the product of this enzyme catalyst reaction.  You can see the…

Organic Chemistry of Metabolic Pathways

Metabolic pathways allude to the arrangement of chemical catalyzed reactions that lead to the transformation of a substance into the final product. Metabolic pathways incorporate a progression of reaction where the substrate is changed continuously and the transitional metabolites are persistently recovered.

Glucogenesis

Glucogenesis is a metabolic pathway in which glucose is produced from carbon substrates that are not carbohydrates. This process is observed in plants, animals, fungi, bacteria and other micro organisms. The general  definition for glucogenesis or gluconeogenesis is as follows,