can you show the step by step mechanism of these stating the neuclophiles and electrophiles and discussing the stereoselectivity? Why is that one has a higher yield then the other? Thank you

Chemistry
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ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
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Chapter1: Chemical Foundations
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Q) can you show the step by step mechanism of these stating the neuclophiles and electrophiles and discussing the stereoselectivity? Why is that one has a higher yield then the other? Thank you

Me
Me
Me
LOH
OTIPS
23
n-BuLi
THF, -78 °C
(85%)
12, NaHCO3
CH₂Cl₂/H₂O
[gram scale]
Me Me
Me
4
OTIPS
24 (45%)
H
+
Me
Me
Me
OTIPS
25 (35%)
NOE
Transcribed Image Text:Me Me Me LOH OTIPS 23 n-BuLi THF, -78 °C (85%) 12, NaHCO3 CH₂Cl₂/H₂O [gram scale] Me Me Me 4 OTIPS 24 (45%) H + Me Me Me OTIPS 25 (35%) NOE
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