In the Lineweaver-Burke plot below, which kinetic parameter(s) change upon addition of an uncompetitive inhibitor? -1/KOPP 1/Vapp max -1/KM O Vmax A/L 0 -1/Vmax O Km O Both Vmax and Km O Neither Vmax nor Km + Uncompetitive inhibitor No inhibitor present 1/[S]

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Chapter1: Chemical Foundations
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In the Lineweaver-Burke plot below, which kinetic parameter(s) change upon addition
of an uncompetitive inhibitor?
-1/KOPP
1/Vapp
max
-1/KM
O Vmax
O Km
1/V
-1/Vmax
Both Vmax and Km
O Neither Vmax nor Km
+ Uncompetitive
inhibitor
No inhibitor
present
1/[S]
Transcribed Image Text:In the Lineweaver-Burke plot below, which kinetic parameter(s) change upon addition of an uncompetitive inhibitor? -1/KOPP 1/Vapp max -1/KM O Vmax O Km 1/V -1/Vmax Both Vmax and Km O Neither Vmax nor Km + Uncompetitive inhibitor No inhibitor present 1/[S]
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