Match the following proteins to their functions ✓ Cathepsins ✓ Calpains ✓ Granzyme B ✓ Apoptosis inducing factor ✓ Apaf-1 • Bax - A. Cleaves iCAD, leading to DNA fragmentation B. A component of the apoptosome that results in the activation of pro-caspase 9 C. Activation of caspase 12 in response to increased intracellular Ca2+ D. Homodimers form pores in the outer membrane of the mitochondria E. A mitochondrial flavoprotein that induces chromatin condensation and DNA fragmentation F. Mitochondrial permeability, externalization of phosphatidylserine on the plasma membrane of apoptotic cells

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A:

Genomic studies

Genomic studies (genomics) is the study of the whole genome of an organism. Using bioinformatics and high-performance computing, genomic researchers examined massive amounts of deoxyribonucleic acid (DNA)-sequence data to discover variations or mutations that affect drug response, health, or disease. Genomics is a much younger discipline than genetics, having only emerged in the last few decades as a result of technological advancements in DNA sequencing and computational biology.