Let's suppose that a normal chromosome carries genes labeled A through /. The centromere is located between genes B and C. As shown below, a chromosome with an inversion has a region where the order of certain genes is reversed. Note: The genes on the inverted chromosome carry recessive alleles that are designated with lowercase letters. Normal chromosome: A B Centromere C D E F G H I Chromosome with an inversion: a b Centromere c d h g fei A. If you ignore possible fertility issues, do you think this individual will otherwise be phenotypically normal or abnormal? Explain why. B. Let's suppose a single crossover during meiosis occurs between these two homologs in the region between genes F and G (and between g and f). Following the crossover, what is the order of genes (designated with upper and lower case letters) on the two resulting chromosomes. Include centromeres in your answer. Hint: Both of the resulting chromosomes will carry gene deletions and gene duplications.

Human Heredity: Principles and Issues (MindTap Course List)
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Chapter6: Cytogenetics: Karyotypes And Chromosome Aberrations
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Problem 14QP: Variations in Chromosome NumberAneuploidy Describe the process of nondisjunction and explain when it...
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Let's suppose that a normal chromosome carries genes labeled A through /. The centromere is located between genes B and C. As shown below, a
chromosome with an inversion has a region where the order of certain genes is reversed. Note: The genes on the inverted chromosome carry recessive
alleles that are designated with lowercase letters.
Normal chromosome:
A B Centromere C D E F G H I
Chromosome with an inversion:
a
b Centromere c d h g fei
A. If you ignore possible fertility issues, do you think this individual will otherwise be phenotypically normal or abnormal? Explain why.
B. Let's suppose a single crossover during meiosis occurs between these two homologs in the region between genes F and G (and between g and f).
Following the crossover, what is the order of genes (designated with upper and lower case letters) on the two resulting chromosomes. Include centromeres
in your answer. Hint: Both of the resulting chromosomes will carry gene deletions and gene duplications.
Transcribed Image Text:Let's suppose that a normal chromosome carries genes labeled A through /. The centromere is located between genes B and C. As shown below, a chromosome with an inversion has a region where the order of certain genes is reversed. Note: The genes on the inverted chromosome carry recessive alleles that are designated with lowercase letters. Normal chromosome: A B Centromere C D E F G H I Chromosome with an inversion: a b Centromere c d h g fei A. If you ignore possible fertility issues, do you think this individual will otherwise be phenotypically normal or abnormal? Explain why. B. Let's suppose a single crossover during meiosis occurs between these two homologs in the region between genes F and G (and between g and f). Following the crossover, what is the order of genes (designated with upper and lower case letters) on the two resulting chromosomes. Include centromeres in your answer. Hint: Both of the resulting chromosomes will carry gene deletions and gene duplications.
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