Knowing that the genetic code is almost universal, a scientist uses molecular biological methods to insert the human - globin gene (shown in the figure below (Links to an external site.)) into bacterial cells, hoping the cells will express it and synthesize functional - globin protein. Instead, the protein produced is nonfunctional and is found to contain many fewer amino acids than does -globin made by a eukaryotic cell. Explain why and give thoughts as to how to overcome this.

Q: I are studying pancreatic islet cells and have isolated, cloned, and sequenced a novel protein that…

A: A transmembrane refers to a protein or molecule that spans the cell membrane, extending from the…

Q: by Transcription Factor IID (TF IID)

A:

Q: Aminoacyl-tRNA synthetases are the only component of gene expression that decodes the genetic code.…

A: The protein synthesis involves the synthesis of the polypeptide chain which is catalyzed by several…

Q: In describing the triplet binding assay, an undergraduate with limited knowledge of translation…

A: Every three nucleotides in a row count as a triplet in the genetic code and codes for a single amino…

Q: The chemical bisulfite transforms cytosine (C) to uracil (U) (U). In DMSO, bisulfite is dissolved.…

A: Dimethyl sulfoxide is an organosulfur compound with the formula (CH₃)₂SO. The chemical bisulfite…

Q: Assume a bacterial gene underwent a mutation, where a thymine base from an early portion of the…

A: Protein consists of amino acids.

Q: A synthetic mRNA added to a cell-free protein-synthesizing system produces a peptide with the…

A: Translation is the process of formation of protein using the information encoded in the mRNA. mRNA…

Q: Tay Sachs disease is an autosomal recessive disease in which a protein – Hex A - is abnormal. To…

A: Molecular Biology is the branch of biology that deals with a study of the composition, arrangement,…

Q: Part A The bacterial gene little protein (lilP) makes a small protein of 11 animo acids (AA) in…

A: Introduction :  The translated form of the DNA sequence is the amino acid sequence. The DNA sequence…

Q: The disease cystic fibrosis is the result of a mutation in the gene that encodes the cystic fibrosis…

A: A codon is a DNA or RNA trinucleotide sequence encoding a particular amino acid or signaling the…

Q: You are studying a protein that contains the peptide sequence RDGSWKLVI. The part of the DNA…

A: The restriction endonuclease are responsible for cutting the DNA at specific sequence and they…

Q: The restriction endonuclease NciI recognizes and cuts the five-base-pair sequence 5’- CC(G/C)GG-3’…

A: Introduction: A bacterial protein termed restriction enzyme, also known as restriction endonuclease,…

Q: protein. How would the protein produced from sequence #1 differ from the protein produced from…

A: The sequences provided are of a non-coding strand or template strand. mRNA is transcribed…

Q: How many possible mRNAs could be derived from a gene with three exons (exon 1, exon 2, and exon 3)?…

A: Transcription is a process in which one strand of DNA known as template strand is known as converted…

Q: The following fictitious double-stranded bacterial DNA sequence codes for a fictitious prot Both…

A: As per the guidelines, this is a question with multi-subparts, we will solve the first three…

Q: Cystic fibrosis (CF) is an inherited disorder caused by different types of mutations, many of which…

A: CF is caused by a mutation in a gene called the cystic fibrosis transmembrane conductance regulator…

Q: Imagine that you repeat the tRNA Selection experiment with modifications as follows: 1. Synthesize…

A: We know that the amino acid sequence of a polypeptide synthesized with respect to an mRNA is based…

Q: When the cDNA was sequenced by the Sanger method utilizing ddCTP, the following products were…

A: Answer :: If the dCTP was not present, the polymerization would come to a standstill, resulting…

Q: a) Create its complementary strand. b) Show 3 different types of mutation that can happen to this…

A: Humans and nearly all other species contain their genetic information in DNA, also known as…

Genome annotation

The technique of linking biological information to genome sequences is termed genome annotation. Gene annotation is the method of identifying gene locations and coding sections. It helps us understand what these genes are doing in the body through establishing structural characteristics and linking them to the actions of various proteins.