In the pathway below, normal signalling driving cell division requires a mitogen (ligand), an RTK, Ras and proteins X and Y. Which of the following statements is true about the genes that encode the mitogen and Ras in healthy cells? mitogen active Ras protein CYTOSOL GTP active signaling protein Y active receptor active signaling protein X tyrosine kinase CELL DIVISON

Q: Cyclic adenosine monophosphate (CAMP) is a molecule that can act as an allosteric activator of…

A: The second messenger cyclic adenosine monophosphate (cAMP, cyclic AMP, or 3',5'-cyclic adenosine…

Q: for question 1, choose wheater each choice is either tumor suppressor or proto oncogene\ for…

A: Proto-oncogenes and tumor suppressor genes are two types of genes that play important roles in the…

Q: 1) One cell-signaling pathway implicated in the regulation of cell division is the mTOR/Akt pathway.…

A: mTOR/Akt pathway involved in cell division.

Q: Using examples, describe the signalling pathway from receptor tyrosine kinase activation to gene…

A: Many polypeptide growth factors, cytokines, and hormones have high-affinity cell surface receptors…

Q: Which of the following would most likely mimic Rb loss? Rb mutant where the phosphosites are mutated…

A: Rb is a tumor suppressor gene. Loss of function mutation in Rb gene leads to the retinoblastoma and…

Q: a drug that inhibits metastasis, which of the following strategies is the WORST idea O to disrupt…

A: Metastasis is the part of the body that is the initial location of the start of cancerous cells and…

Q: Which of the following is NOT in common between GPCRS and RTKS? Both receptors are activated upon…

A: In the cell plasma membrane, several receptors are present, which help to transfer the extracellular…

Q: Which of the following is a type of signal transduction pathway controlling gene expression? All of…

A: Signal transduction pathways are cascades of signals and crosstalk among various signnals to…

Q: After cutting yourself with a knife while chopping vegetables, your body begins extensive mitosis…

A: The given DNA sequence is as follows,  TAC GGG CAA ACC TCT AGC CCA ATG TCG ATC

Q: Describe what cyclin dependent kinase does in the activation of MPF and how this relates to signal…

A: Cyclin dependent kinase or CDK is catalytic and act as a protein kinase.CDKs are so named because…

Q: Lung cell cancers are often associated with genetic changes in the EGFR/MAPK signaling pathway. One…

A: The cancer occurs in the body because of excessive growth and cell division in the cancer part of…

Q: Match the protein on the left with the mechanism of how the protein is activated on the right.…

A: Proteins can differ in terms of size, charge density, structure, and biological activity. Protein…

Q: What purpose do scaffolding proteins serve in binding to Map kinase enzymes?

A: Introduction :- MAPKs are serine/threonine kinases that activate a variety of cytoplasmic and…

Q: The NF-κB signaling pathway, an important pathway in immune response and inflammation, is shown in…

A: Signaling pathway, is a series of chemical reactions that occur within a biological cell when…

Q: Explain the importance of the termination of cell signaling, and ways this can be accomplished

A: Cell signaling is a complex process by which cells communicate with each other to coordinate their…

Q: Of the steps listed below, which problem would take you the longest to realize you had a problem in…

A: Receptor tyrosine kinases are abbreviated as RTKs.They constitute one class of transmembrane…

Q: A normal cell has no growth factor bound to the growth factor receptor. What do you predict about…

A: The extracellular signal-regulated kinase (ERK) pathway is an important pathway that cells use to…

Q: You've engineered a mutant cell where the FADD adapter was truncated. The mutant FADD only contains…

A: The process of programmed cell death is called apoptosis. Unwanted cells, such as those between a…

Q: Complete the sentences about cell signaling using the words and phrases. (Not all words and phrases…

A: The process by which cells interact with other cells in their body or with the outside environment…

Q: Two protein kinases, barley kinase and hops kinase, function sequentially in an intracellular…

A: The signaling pathway is a chemical or physical signals that is transmitted to a cell through series…

Q: You have discovered two new inhibitors that inhibit enzymes involved in the apoptotic pathway shown…

A: The signaling pathway of cell survival (inhibition of apoptosis): 1. Bad is an apoptotic protein…

Q: Glucocorticoids- Mechanism of Action

A: Glucocorticoids are a type of steroid hormone that is produced naturally by the adrenal glands or is…

Q: Describe HOW/WHY phosphorylation and de-phosphorylation act like an “on/off” switch for the relay…

A: Phosphorylation is the process of adding a phosphate group to a molecule, typically a protein, by a…

Q: This phosphatase removes an inhibitory phosphotyrosine phosphate from serine protein kinase,…

A: For cell proliferation and cell growth, cell division occurs. A cell undergoes a cell cycle before…

Q: All but which of the following best explains the advantage of cancer cells expressing PKM2 over…

A: Cancer refers to abnormal growth of the cells and this they will divide uncontrollably. The cancer…

Q: Mutant tyrosine kinase signaling proteins are implicated in many types of human cancer. Hundreds of…

A: A drug is any chemical substance that causes an adjustment or change of a living being's physiology…

Q: Signaling pathways often require receptor dimers to become active. What would be an advantage of the…

A: Most receptors dimerize during their association with their ligands. This dimerization provides them…

Q: Integrins have many functions, one of which is sensing connections to the extracellular matrix. What…

A: Integrins provide transmembrane connections between the extracellular matrix and the cytoskeleton,…

Q: This TSG targets beta-catenin for degradation and inhibits the Wnt signaling pathway but when it is…

A: These are genes that inhibits cell division of the cell, repair mistakes in DNA or control apoptosis…

Q: Which of the following is NOT an example of allosteric regulation? Select an answer and submit. For…

A: Allosteric regulation is depend on the enzyme active site binding molecule that produce confirmation…

Q: mediated signaling without ligand, suggesting the signaling pathway has been constitutively…

A: Receptor tyrosine kinase is involved is cell signal transduction by a ligand it is responsible for…

Q: that binds Fsh3 is a receptor tyrosine kinase (RTK) and there are numerous fish tumor cell lines…

A: Answer. Enzyme-linked receptors are a second major type of cell surface receptors. Like…

Q: Notch signaling orchestrates transition from G1 to S phase of cell cycle by multiple other…

A: Notch signaling is a profoundly conserved cell communication pathway that plays an essential part in…

Q: You established two cell lines (Cell line X and Cell line Y) from colon cancer patients and both of…

A: Wnt Signalling Pathways Are A Collection Of Signal Transduction Pathways That Start With Proteins…

Q: Isothiocyanates are compounds found in vegetables such as broccoli. Such compounds have been shown…

A: The cervix is the lowermost section of the uterus and when a malignant tumour appear here, it’s…

Q: Is the regulation shown (denoted by?) positive or negative regulation? Explain why the type of…

A: A feedback loop is a biological process wherein the output or the final product of a system…

Cancer Therapy