In E. coli, three structural genes (A, D, and E) encode enzymes A, D, and E, respectively. Sequence O is an operator. The sequences are in the order O- A- D- E on the chromosome. The three enzymes encoded by A, D, and E catalyze the biosynthesis of valine. Mutations at the A, D, E, and O were isolated to study the production of enzymes A, D, and E when cellular levels of valine were low (T. Ramakrishnan and E. A. Adelberg. 1965. Journal of Bacteriology 89:654-660). Amounts of the enzymes produced by partial-diploid E. coli with various combinations of mutations are shown in the following table. Amount of enz produced Genotype E D E* D* A* O*/E* D* 1. 2,40 2.00 A* O* E* D* A* O"/E* D* 2. 35.80 38.60 A* O* E* D A* O I 3. E* D* A" O* 1.80 1.00 E* D* A O / 4. 35.30 38.00 E* D A* O* E D* A* O / 5. 2.38 38.00 E* D A* O*
In E. coli, three structural genes (A, D, and E) encode enzymes A, D, and E, respectively. Sequence O is an operator. The sequences are in the order O- A- D- E on the chromosome. The three enzymes encoded by A, D, and E catalyze the biosynthesis of valine. Mutations at the A, D, E, and O were isolated to study the production of enzymes A, D, and E when cellular levels of valine were low (T. Ramakrishnan and E. A. Adelberg. 1965. Journal of Bacteriology 89:654-660). Amounts of the enzymes produced by partial-diploid E. coli with various combinations of mutations are shown in the following table. Amount of enz produced Genotype E D E* D* A* O*/E* D* 1. 2,40 2.00 A* O* E* D* A* O"/E* D* 2. 35.80 38.60 A* O* E* D A* O I 3. E* D* A" O* 1.80 1.00 E* D* A O / 4. 35.30 38.00 E* D A* O* E D* A* O / 5. 2.38 38.00 E* D A* O*
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Propose an explanation for the small amount of enzyme E produced by genotype 3.
![In E. coli, three structural genes (A, D, and E) encode enzymes A, D,
and E, respectively. Sequence O is an operator. The sequences are in the
order O- A- D- E on the chromosome. The three enzymes encoded by A,
D, and E catalyze the biosynthesis of valine. Mutations at the A, D, E,
and O were isolated to study the production of enzymes A, D, and E
when cellular levels of valine were low (T. Ramakrishnan and E. A.
Adelberg. 1965. Journal of Bacteriology 89:654-660). Amounts of the
enzymes produced by partial-diploid E. coli with various combinations
of mutations are shown in the following table.
Amount of enz
produced
Genotype
E
D
E* D* A* O*/E* D*
1.
2,40
2.00
A* O*
E* D* A* O"/E* D*
2.
35.80
38.60
A* O*
E* D A* O I
3.
E* D* A" O*
1.80
1.00
E* D* A O /
4.
35.30
38.00
E* D A* O*
E D* A* O /
5.
2.38
38.00
E* D A* O*](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F027ec327-c2ce-4fe8-b7f5-2126e022415b%2F1676c362-474e-4b59-a6cf-2a0118724139%2Fhj5waep.jpeg&w=3840&q=75)
Transcribed Image Text:In E. coli, three structural genes (A, D, and E) encode enzymes A, D,
and E, respectively. Sequence O is an operator. The sequences are in the
order O- A- D- E on the chromosome. The three enzymes encoded by A,
D, and E catalyze the biosynthesis of valine. Mutations at the A, D, E,
and O were isolated to study the production of enzymes A, D, and E
when cellular levels of valine were low (T. Ramakrishnan and E. A.
Adelberg. 1965. Journal of Bacteriology 89:654-660). Amounts of the
enzymes produced by partial-diploid E. coli with various combinations
of mutations are shown in the following table.
Amount of enz
produced
Genotype
E
D
E* D* A* O*/E* D*
1.
2,40
2.00
A* O*
E* D* A* O"/E* D*
2.
35.80
38.60
A* O*
E* D A* O I
3.
E* D* A" O*
1.80
1.00
E* D* A O /
4.
35.30
38.00
E* D A* O*
E D* A* O /
5.
2.38
38.00
E* D A* O*
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