If the nonsense mutation is in the last exon of the mRNA, the result would be: nonsense-mediated decay truncated mRNA a splice variant no expression

Human Heredity: Principles and Issues (MindTap Course List)
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Chapter9: Gene Expression And Gene Regulation
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Problem 8QP: The following segment of DNA codes for a protein. The uppercase letters represent exons. The...
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If the nonsense mutation is in the last exon of the mRNA, the result would be:
nonsense-mediated decay
truncated mRNA
a splice variant
O no expression
Transcribed Image Text:If the nonsense mutation is in the last exon of the mRNA, the result would be: nonsense-mediated decay truncated mRNA a splice variant O no expression
Which statement about nonsense mediated decay (NMD) is false?
O detects MRNAS containing premature termination codons and degrades them
depends on the presence of exon junction complex (EJC) attached next to splice
sites
O It occurs during the first (“pioneer") round of translation
O it is triggered by the ribosome-TRNA complex
Transcribed Image Text:Which statement about nonsense mediated decay (NMD) is false? O detects MRNAS containing premature termination codons and degrades them depends on the presence of exon junction complex (EJC) attached next to splice sites O It occurs during the first (“pioneer") round of translation O it is triggered by the ribosome-TRNA complex
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