The information content of the genome includes binding sites Regulatory RNA Ribosome binds MRNA. TRNAS bind protein binds DNA. polymerase binds DNA. each codon in MRNA. Spliceosome binds primary RNA transcript. Translation- termination protein binds MRNA. Poly(A) polymerase binds primary RNA transcript. 5' UTR Intron Exon 3' UTR Codons Codons Codons Transcription regulatory element Translation termination site Promoter Translation initiation site 5' splice site 3' splice site Polyadenylation site FIGURE 14-9 A gene within DNA may be viewed as a series of binding sites for proteins and RNAS. that encode proteins and RNAS, plus the binding sites that govern the time and place of their actions. As a genome draft continues to be improved, the principal objective is the identification of all of the functional elements of the genome. This process is referred to as annotation.
Proteins
We generally tend to think of proteins only from a dietary lens, as a component of what we eat. However, they are among the most important and abundant organic macromolecules in the human body, with diverse structures and functions. Every cell contains thousands and thousands of proteins, each with specific functions. Some help in the formation of cellular membrane or walls, some help the cell to move, others act as messages or signals and flow seamlessly from one cell to another, carrying information.
Protein Expression
The method by which living organisms synthesize proteins and further modify and regulate them is called protein expression. Protein expression plays a significant role in several types of research and is highly utilized in molecular biology, biochemistry, and protein research laboratories.
In Figure 14-9, how are the positions of codons
determined?
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