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Iculate the actual, physiological deltaG for the reaction Phosphocreatine + ADP > creatine + ATP at 35.61°C, as it occurs in the cylosol of 59 mM, creatine at 1.67 mM, ADP at 0.75 mM, and ATP at 2.49 mM. Give the answer in kJ/mol to one decimal place. The standard deltaG hydrolysis of phospho eurons, wiul p 72 Jllmel nnd tho ctandard deltaG for the nhosnhorylation of ADP with Pi is +35.05 kJ/mol. Give the answer in KJ/mol to one decimal place.

Iculate the actual, physiological deltaG for the reaction Phosphocreatine + ADP > creatine + ATP at 35.61°C, as it occurs in the cylosol of 59 mM, creatine at 1.67 mM, ADP at 0.75 mM, and ATP at 2.49 mM. Give the answer in kJ/mol to one decimal place. The standard deltaG hydrolysis of phospho eurons, wiul p 72 Jllmel nnd tho ctandard deltaG for the nhosnhorylation of ADP with Pi is +35.05 kJ/mol. Give the answer in KJ/mol to one decimal place.

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
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QUESTION 1 Calculate the actual, physiological deltaG for the reaction Phosphocreatine + ADP > creatine +ATP at 35.61°C, as it occurs in the cytosol of neurons, with phosphocreatine at 4.69 mM, creatine at 1.67 mM, ADP at 0.75 mM, and ATP at 2.49 mM. Give the answer in kJ/mol to one decimal place The standard deltaG hydrolysis of phosphocreatine with H20 is -46.73 kJ/mol and the standard deltaG for the phosphorylation of ADP with Pi is +35.05 kJ/mol. Give the answer in kJ/mol to one decimal place. You may find these constants useful: Physical constants and Units Used in Thermodynamics (link opens in new page) QUESTION 2 Calculate the standard free-energy change of the reaction catalysed by the enzyme phosphoglucomutase Glucose-1-P Glucose-6-P, given that, starting with 38.25 mM Glucose-1-P and no Glucose-6-P, the final equilibrium mixture at 25C and pH=7 0 contains 8.06 mM Glucose-6-P and the remaining Glucose-1-P. Give the answer in J/mol.K to one decimal place. You may find these constants useful: Physical constants and Units Used in Thermodynamics (link opens in new page)
Transcribed Image Text:QUESTION 1 Calculate the actual, physiological deltaG for the reaction Phosphocreatine + ADP > creatine +ATP at 35.61°C, as it occurs in the cytosol of neurons, with phosphocreatine at 4.69 mM, creatine at 1.67 mM, ADP at 0.75 mM, and ATP at 2.49 mM. Give the answer in kJ/mol to one decimal place The standard deltaG hydrolysis of phosphocreatine with H20 is -46.73 kJ/mol and the standard deltaG for the phosphorylation of ADP with Pi is +35.05 kJ/mol. Give the answer in kJ/mol to one decimal place. You may find these constants useful: Physical constants and Units Used in Thermodynamics (link opens in new page) QUESTION 2 Calculate the standard free-energy change of the reaction catalysed by the enzyme phosphoglucomutase Glucose-1-P Glucose-6-P, given that, starting with 38.25 mM Glucose-1-P and no Glucose-6-P, the final equilibrium mixture at 25C and pH=7 0 contains 8.06 mM Glucose-6-P and the remaining Glucose-1-P. Give the answer in J/mol.K to one decimal place. You may find these constants useful: Physical constants and Units Used in Thermodynamics (link opens in new page)
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