Polyisocyanates are involved in the induction of the full spectrum of hypersensitivity responses and nonimmune inflammatory reactions including asthma. Which of the following statement is not correct with respect to these observations and impact on immunity?

Human Anatomy & Physiology (11th Edition)
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Chapter1: The Human Body: An Orientation
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Polyisocyanates are involved in the induction of the full spectrum of hypersensitivity responses and nonimmune inflammatory reactions including asthma. Which of the following statement is not correct with respect to these observations and impact on immunity?

a. A person once sensitized to polyisocyanate can demonstrate group reactivity to this set of compounds.

b. Individuals having an acute exposure to toluene diisocyanate is more likely to develop hypersensitivity then individuals chronically exposed to low vapor levels.

c. A mechanism for this hypersensitivity is the toluene diisocyanate forms a covalent bond with proteins that are part of the airway resulting in the immune system developing a response to “self” proteins.

d. Adaptive immunity can interact or “message” the Innate immune system to up or down regulate its expression.

e. All of the statements are correct.

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