How does the signaling cascade initiated by activation of the Gas protein enter the nucleus to trigger the transcription ofcyclic AMP responsive genes?O A. Phosphorylated CREB is transported across the nuclear envelope in COPIIl coated vesicles.B. CAMP enters the nucleus through nuclear pores.C. Gas diffuses into the nucleus to bind and activate its nuclear receptor.O D. Activated PKA enters the nucleus through nuclear pores.

Answered: How does the signaling cascade…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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How does the signaling cascade initiated by activation of the Gas protein enter the nucleus to trigger the transcription of
cyclic AMP responsive genes?
O A. Phosphorylated CREB is transported across the nuclear envelope in COPIIl coated vesicles.
B. CAMP enters the nucleus through nuclear pores.
C. Gas diffuses into the nucleus to bind and activate its nuclear receptor.
O D. Activated PKA enters the nucleus through nuclear pores.

Expert Solution

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Signal transduction requires a receptor through which a ligand interacts and transmits its information to activate several other downstream signaling molecules which ultimately run an entire signaling cascade to finally generate a response by specific expression of a gene.

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