How does NF-κB induce gene expression? a. A small, hydrophobic ligand binds to NF-κB, activating it. b. Phosphorylation of the inhibitor Iκ-B dissociates the complex between it and NF-κB, and allows NF- κB to enter the nucleus and stimulate transcription. c. NF-κB is phosphorylated and is then free to enter the nucleus and bind DNA. d. NF-κB is a kinase that phosphorylates a transcription factor that binds DNA and promotes protein production.
Gene Interactions
When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.
Gene Expression
Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.
How does NF-κB induce gene expression?
a. A small, hydrophobic ligand binds to NF-κB,
activating it.
b. Phosphorylation of the inhibitor Iκ-B dissociates
the complex between it and NF-κB, and allows NF-
κB to enter the nucleus and stimulate
transcription.
c. NF-κB is phosphorylated and is then free to enter
the nucleus and bind DNA.
d. NF-κB is a kinase that phosphorylates a
transcription factor that binds DNA and promotes
protein production.
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