"he equation p + 2pq + q° = 1 representing the lardy-Weinberg proportions examines genes with nly two alleles in a population. . Derive a similar equation describing the equilib- rium proportions of genotypes for a gene with three alleles. [Hint: Remember that the Hardy- Weinberg equation can be written as the binomial expansion (p + q)*.] A single gene with three alleles (r^, 1", and i) is responsible for the ABO blood groups. Individuals with blood type A can be either rr or ^ i; those with blood type B can be either 1" 1 or 1" i; people with AB blood are A ", and type O individuals are ii. Among Armenians, the frequency of is 0.360, the frequency of " is 0.104, and the frequency of i
Genetic Variation
Genetic variation refers to the variation in the genome sequences between individual organisms of a species. Individual differences or population differences can both be referred to as genetic variations. It is primarily caused by mutation, but other factors such as genetic drift and sexual reproduction also play a major role.
Quantitative Genetics
Quantitative genetics is the part of genetics that deals with the continuous trait, where the expression of various genes influences the phenotypes. Thus genes are expressed together to produce a trait with continuous variability. This is unlike the classical traits or qualitative traits, where each trait is controlled by the expression of a single or very few genes to produce a discontinuous variation.
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