You have isolated a true-breeding fish strain that has blue scales. Then you isolate another true- breeding fish strain that that has orange scales. You know that each of the colors are caused by recessive alleles in 2 different genes. You cross a blue fish to an orange fish and find out that all of the offspring have orange looking scales. You cross the Fi progeny with each other and find 37 fish blue scales, 27 fish have green scales, and 98 fish have orange scales. You suspect that the inheritance pattern is due to recessive epistasis. Draw the order of the phenotypes controlled by this biochemical pathway that would be consistent with your һypothesis. а.

Human Anatomy & Physiology (11th Edition)
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Chapter1: The Human Body: An Orientation
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You have isolated a true-breeding fish strain that has blue scales. Then you isolate another true-
breeding fish strain that that has orange scales. You know that each of the colors are caused by
recessive alleles in 2 different genes.
You cross a blue fish to an orange fish and find out that all of the offspring have orange looking
scales. You cross the Fi progeny with each other and find 37 fish blue scales, 27 fish have green
scales, and 98 fish have orange scales.
You suspect that the inheritance pattern is due to recessive epistasis. Draw the order of the
phenotypes controlled by this biochemical pathway that would be consistent with your
һурothesis.
а.
b. Carry out a statistical analysis to determine if the ratio of orange to green to blue scaled
fish in the F2 generation is consistent to recessive epistasis inheritance pattern.
Phenotypes
Observed F2
Chi-square
Нуpothesized
Phenotypic ratio
Expected
numbers
Total :
Degrees of
freedom :
Conclusion :
Transcribed Image Text:You have isolated a true-breeding fish strain that has blue scales. Then you isolate another true- breeding fish strain that that has orange scales. You know that each of the colors are caused by recessive alleles in 2 different genes. You cross a blue fish to an orange fish and find out that all of the offspring have orange looking scales. You cross the Fi progeny with each other and find 37 fish blue scales, 27 fish have green scales, and 98 fish have orange scales. You suspect that the inheritance pattern is due to recessive epistasis. Draw the order of the phenotypes controlled by this biochemical pathway that would be consistent with your һурothesis. а. b. Carry out a statistical analysis to determine if the ratio of orange to green to blue scaled fish in the F2 generation is consistent to recessive epistasis inheritance pattern. Phenotypes Observed F2 Chi-square Нуpothesized Phenotypic ratio Expected numbers Total : Degrees of freedom : Conclusion :
Table 1: Probability table of chi-square values
Probabilities
df
0.99
0.95
0.90
0.70
0.50
0.30
0.20
0.10
0.05
0.01
0.001
1
0.0001
0.004
0.016
0.15
0.46
1.07
1.64
2.71
3.84
6.64
10.83
2
0.02
0.10
0.21
0.71
1.39
2.41
3.22
4.61
5.99
9.21
13.82
3
0.12
0.35
0.58
1.42
2.37
3.67
4.64
6.25
7.82
11.35
16.27
4
0.30
0.71
1.06
2.20
3.36
4.88
5.99
7.78
9.49
13.28
18.47
5
0.55
1.15
1.61
3.00
4.35
6.06
7.29
9.24
11.07
15.09
20.52
0.87
1.64
2.20
3.83
5.35
7.23
8.56 10.65
12.59
16.81
22.46
7
1.24
2.17
2.83
4.67
6.35
8.38
9.80
12.02
14.07
18.48
24.32
Transcribed Image Text:Table 1: Probability table of chi-square values Probabilities df 0.99 0.95 0.90 0.70 0.50 0.30 0.20 0.10 0.05 0.01 0.001 1 0.0001 0.004 0.016 0.15 0.46 1.07 1.64 2.71 3.84 6.64 10.83 2 0.02 0.10 0.21 0.71 1.39 2.41 3.22 4.61 5.99 9.21 13.82 3 0.12 0.35 0.58 1.42 2.37 3.67 4.64 6.25 7.82 11.35 16.27 4 0.30 0.71 1.06 2.20 3.36 4.88 5.99 7.78 9.49 13.28 18.47 5 0.55 1.15 1.61 3.00 4.35 6.06 7.29 9.24 11.07 15.09 20.52 0.87 1.64 2.20 3.83 5.35 7.23 8.56 10.65 12.59 16.81 22.46 7 1.24 2.17 2.83 4.67 6.35 8.38 9.80 12.02 14.07 18.48 24.32
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